Results 201 to 210 of about 66,500 (291)
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
International Journal of NanomedicineDaewon Han,1,2,* Hyeji Lee,1,* Solji Lee,1 Kyubae Lee,3 Nam-Kyung Lee,4,5 Tae-Eun Jin,6 Junguee Lee,7 Jong-Seok Kim,1,2 Do Kyung Kim,8 Jongdae Shin,1,2 Hwan-Woo Park1,2 1Department of Cell Biology, Konyang University College of Medicine ...
Han D +10 more
doaj
Journal of Intelligent Medicine, EarlyView.Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan +3 more
wiley +1 more source
Journal of Intelligent Medicine, EarlyView.Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source
Mechanistic Target of Rapamycin Complex 1 Promotes the Expression of Genes Encoding Electron Transport Chain Proteins and Stimulates Oxidative Phosphorylation in Primary Human Trophoblast Cells by Regulating Mitochondrial Biogenesis. [PDF]
Sci Rep, 2019 Rosario FJ +6 more
europepmc +1 more source
Journal of Periodontology, EarlyView.Abstract Historically, immunological memory was considered an exclusive feature of adaptive immunity. However, innate immune cells have recently been shown to record and maintain epigenetically imprinted memory of earlier infectious or inflammatory challenges.
George Hajishengallis
wiley +1 more source
, 2015 Adhesion of cells to the surrounding extracellular matrix (ECM) is required for a metazoan existence, enabling cells to migrate and signal appropriately in response to changes in their environment. Plasma membrane integrin receptors are key mediators of cell-ECM adhesion: they bind a range of ECM molecules at focal sites, trigger the recruitment of ...
openaire +1 more source
BMI and Breast Subcutaneous Fat
Journal of Ultrasound in Medicine, EarlyView.Objectives Obesity is closely associated with the occurrence and progression of breast cancer. While body mass index (BMI) is widely used to diagnose obesity, it has certain limitations. Subcutaneous fat thickness (SFT) also serves as an indicator of body composition. However, studies on breast SFT are scarce.
Shiyu Wang +5 more
wiley +1 more source
Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng +6 more
wiley +1 more source