Results 91 to 100 of about 110,958 (307)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Modeling of operational performance parameters applied in mechanized harvest of coffee
Revista Brasileira de Engenharia Agrícola e AmbientalIn super-mechanized coffee harvesting system, all operations are performed mechanically. In order to improve the logistics of mechanized agricultural operations, the knowledge on the variables that affect the operational performance can generate models ...
João P. B. Cunha +3 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
History and progress in rice research and its future perspective in Cambodia
Plant Production ScienceSince 1993, rice production in Cambodia has increased fivefold, positioning it as a key player in global food security through its export contributions.
Kazuki Saito +8 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Conceptual mechanization studies for a horizon definition spacecraft communications and data handling subsystem [PDF]
Conceptual mechanization for horizon definition spacecraft communications and data handling ...
Hartman, D. J., Kahnke, J., Kirk, R. J.
core +1 more source
Développer durablement la mécanisation pour améliorer la productivité de l'agriculture familiale en Afrique Subsaharienne [PDF]
, 2015 In sub-Saharan Africa (SSA), the agricultural production energy is supplied by men (65%), animals (25%) and motor (10%). Family farming, more than 75% of farms, provides relevant incomes of rural populations but are often considered as unproductive ...
Havard, Michel, Side, Claude Stéphane
core
FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source