Results 81 to 90 of about 36,809 (300)
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
The Status of Labor-Saving Mechanization in Fruits and Vegetables [PDF]
The objective of this paper is to examine the status of labor-saving mechanization in U.S. fruit and vegetable harvesting. Fruit and vegetable harvest mechanization has several potential advantages: reduced harvest costs, eliminate problems associated ...
Wallace E. Huffman
core
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Exploring mechanization degree and capacity in Malaysia’s oil palm plantations [PDF]
, 2021 Development of mechanization is a crucial element in oil palm plantations in Malaysia since its significant role in reducing highly dependence on manual workers.
Darius El Pebrian +1 more
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Higher Education Without Commodification, Mechanization or Moralization [PDF]
Journal of Philosophical InvestigationsWhat is the ultimate end of higher education? Giambattista Vico, echoing Socrates’s Delphic oracle, claimed that the ultimate end of all education is self-knowledge.
Robert Hanna
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Jurnal Riset PerkebunanCoconut (Cocos nucifera) plays a crucial role in agricultural economies, particularly in coconut-producing regions, where traditional de-husking methods are labor-intensive and time-consuming. This study focuses on the design, fabrication, and evaluation
Jide Olusegun Adedipe
doaj +1 more source