Results 181 to 190 of about 35,268 (338)

Modeling and Simulation of the Effects of Cyclic Loading on Articular Cartilage Lesion Formation

, 2013
We present a model of articular cartilage lesion formation to simulate the effects of cyclic loading. This model extends and modifies the reaction-diffusion-delay model by Graham et al.
Ayati, Bruce P., Brouillete, Marc J., Graham, Jason M., Martin, James A., Ramakrishnan, Prem S., Wang, Xiayi   +5 more
core  

Cancer mechanobiology: Effects and therapeutic perspectives [PDF]

, 2017
Antonios N. Gargalionis, Efthimia K. Basdra, Athanasios G. Papavassiliou   +2 more
openalex   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

Resilient Biophysical Phenotype of Memory CD4+ T Cells in Long‐Lived Mice

Immunology, EarlyView.
Aging is associated with increased stiffness and reduced migratory capacity of memory CD4+ T cells; however, these biophysical declines do not persist in exceptionally long‐lived mice. Instead, long‐lived individuals preserve T cell mechanics, migration and intracellular architecture, supporting mechanical resilience as a hallmark of successful immune ...
Aldo Abarca‐Ortega, Blanca González‐Bermúdez, Judith Félix‐Escalera, Mónica González‐Sánchez, Enzo Brito, Mónica De la Fuente, Gustavo R. Plaza   +6 more
wiley   +1 more source

The Role of Wnt Signaling in Age‐Related Alveolar Bone Loss and Regeneration

Journal of Periodontal Research, EarlyView.
The graphical abstract summarizes key signaling pathways involved in bone formation and resorption associated with Wnt signaling across young and aged long bone and jaw tissues. Levels of evidence are indicated as robust, moderate, or emerging, reflecting the current experimental support in each context.
Hsiao H. Sung, Navya Chalamalasetty, Ali Alzainal, Hanlong Liu, Lexuan Wang, Pietra Colacrai Arikita, Ivy C. X. Wei, Hom‐Lay Wang, M. H. J. van den Bosch, Michelle S. Caird, Peter M. van der Kraan, Kenneth M. Kozloff, Esmeralda Blaney Davidson   +12 more
wiley   +1 more source

Mechanobiology in the Third Dimension [PDF]

, 2018
Cells are mechanically coupled to their extracellular environments, which play critical roles in both communicating the state of the mechanical environment to the cell as well as in mediating cellular response to a variety of stimuli.
Pedersen, John, Swartz, Melody
core  

Differential Organization of Airway Smooth Muscle Cells on Tubular Surface as A Novel Mechanobiology Mechanism of Airway Tissue Morphogenesis

, 2019
Linhong Deng, Yang Jin, Mingzhi Luo
openalex   +1 more source

An Analysis of Wrist Motions During Daily Activities From a Directional Perspective: The Significance of Directions Beyond the Dart‐Throwing Motion

Orthopaedic Surgery, Volume 17, Issue 5, Page 1486-1502, May 2025.
The study using an optical capture system revealed the directional characteristics of wrist functional motion. The results highlighted the directional range of motion (ROM), differences in preferences between genders and age groups, and identified three key directions most frequently utilized. ABSTRACT Background Previous studies on Activities of Daily
Qipei Wei, Shijie Jia, Shengfang Zhang, Xiaofeng Qiao, Zhixin Wang, Chang Liu, Shanlin Chen   +6 more
wiley   +1 more source

The epidermis coordinates multi-scale symmetry breaking in chiral root growth

Nature Communications
Twisted growth serves myriad adaptive functions in plants. Unlike animal motions, plant motions require symmetry breaking during growth and typically involve microtubule-related genes.
Natasha Nolan, Leila Jaafar, Yuanwei Fan, Yuxuan Huang, Lily Murchison, Juliana Ocasio, Joyce G. Onyenedum, Charles T. Anderson, Guy M. Genin, Ram Dixit   +9 more
doaj   +1 more source

Mechanobiology of initial pseudarthrosis formation with oblique fractures [PDF]

, 2001
Elizabeth G. Loboa, Gary S. Beaupré, Dennis R. Carter   +2 more
openalex   +1 more source