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Transformative biomechanics and mechanobiology breakthroughs shaping the future of health and medicine. [PDF]
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Journal of Biomechanics, 2006
Tendons are able to respond to mechanical forces by altering their structure, composition, and mechanical properties--a process called tissue mechanical adaptation. The fact that mechanical adaptation is effected by cells in tendons is clearly understood; however, how cells sense mechanical forces and convert them into biochemical signals that ...
James Wang
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Tendons are able to respond to mechanical forces by altering their structure, composition, and mechanical properties--a process called tissue mechanical adaptation. The fact that mechanical adaptation is effected by cells in tendons is clearly understood; however, how cells sense mechanical forces and convert them into biochemical signals that ...
James Wang
exaly +3 more sources
Integrative Biology, 2015
Guest editors G. V. Shivashankar, Michael Sheetz and Paul Matsudaira introduce the Mechanobiology themed issue of Integrative Biology.
G V, Shivashankar +2 more
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Guest editors G. V. Shivashankar, Michael Sheetz and Paul Matsudaira introduce the Mechanobiology themed issue of Integrative Biology.
G V, Shivashankar +2 more
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Aging Clinical and Experimental Research, 2013
Bone is a tissue that dynamically adapts mass and architecture to the mechanical loads that occur in daily life in a world with gravity. Bone architecture and mass are influenced by the applied tension peak, whereas the bone formation rate is modulated by the stimulus frequency.
IOLASCON, Giovanni +2 more
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Bone is a tissue that dynamically adapts mass and architecture to the mechanical loads that occur in daily life in a world with gravity. Bone architecture and mass are influenced by the applied tension peak, whereas the bone formation rate is modulated by the stimulus frequency.
IOLASCON, Giovanni +2 more
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2023
Abstract Growth, motion, morphogenesis, and self-organization are features common to all biological systems. Harnessing chemical energy allows biological cells to function out of thermodynamic equilibrium and to alter their number, size, shape, and location. For example, the zygote that results when a mammalian egg and sperm cell fuse
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Abstract Growth, motion, morphogenesis, and self-organization are features common to all biological systems. Harnessing chemical energy allows biological cells to function out of thermodynamic equilibrium and to alter their number, size, shape, and location. For example, the zygote that results when a mammalian egg and sperm cell fuse
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Wound Repair and Regeneration, 2011
ABSTRACTThe mechanophysiological conditions of injured skin greatly influence the degree of scar formation, scar contracture, and abnormal scar progression/generation (e.g., keloids and hypertrophic scars). It is important that scar mechanobiology be understood from the perspective of the extracellular matrix and extracellular fluid, in order to ...
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ABSTRACTThe mechanophysiological conditions of injured skin greatly influence the degree of scar formation, scar contracture, and abnormal scar progression/generation (e.g., keloids and hypertrophic scars). It is important that scar mechanobiology be understood from the perspective of the extracellular matrix and extracellular fluid, in order to ...
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Mechanobiology of Tumor Growth
Chemical Reviews, 2018Over the past decade, researchers have highlighted the importance of mechanical cues of the metastatic niche such as matrix stiffness, topography, mechanical stresses, and deformation on cells in influencing tumor growth and proliferation. Understanding the cellular and molecular basis and fine-tuning the mechano-response of cancer cells to this niche ...
Parthiv Kant Chaudhuri +2 more
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From biomechanics to mechanobiology
Biorheology: The Official Journal of the International Society of Biorheology, 2002Biomechanics can be defined as the application of mechanical concepts to the living world, and various fields of research have been developed such as the mechanics of movement, ergonomics, the mechanical properties of cells and tissues, and the relationship between physiology and applied forces. In this paper, the authors give, through several examples,
J-F, Stoltz, X, Wang
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