Results 71 to 80 of about 14,518 (256)

Solvent-free copper-catalyzed click chemistry for the synthesis of novel N-heterocyclic hybrids based on quinolone and 1, 2, 3-triazole [PDF]

open access: yes, 2017
Copper-catalyzed mechanochemical click reactions have been successfully implemented to provide novel 6-phenyl-2- (trifluoromethyl)quinolones with phenyl-1, 2, 3- triazole moiety at O-4 of quinolone core. Milling procedures utilizing CuI and brass milling
Cetina, Mario   +8 more
core   +6 more sources

Increase of solubility and transmembrane permeability of niclosamide from its mechanochemically synthesized solid dispersions

open access: yesChimica Techno Acta, 2023
More than 4.5 billion people worldwide are affected by parasitic diseases, with helminth infections accounting for 99% of the total number. Niclosamide (NS) is a weakly acidic active pharmaceutical ingredient (API) used to treat helminth infections ...
Elizaveta S. Meteleva   +2 more
doaj   +1 more source

A permeabilized cell model for studying cell division: a comparison of anaphase chromosome movement and cleavage furrow constriction in lysed PtK1 cells. [PDF]

open access: yes, 1981
After lysis in a Brij 58-polyethylene glycol medium, PtK1 cells are permeable to small molecules, such as erythrosin B, and to proteins, such as rhodamine-labeled FAB, myosin subfragment-1, and tubulin.
CANDE, W. Zacheus   +2 more
core   +2 more sources

Mechanochemistry-Directed Ligand Design: Development of a High-Performance Phosphine Ligand for Palladium-Catalyzed Mechanochemical Organoboron Cross-Coupling.

open access: yesJournal of the American Chemical Society, 2023
Mechanochemical synthesis that uses transition-metal catalysts has attracted significant attention due to its numerous advantages, including low solvent waste, short reaction times, and the avoidance of problems associated with the low solubility of ...
Tamae Seo, K. Kubota, Hajime Ito
semanticscholar   +1 more source

Mechanochemistry of the kinesin-1 ATPase [PDF]

open access: yes, 2016
Kinesins are P-loop NTPases that can do mechanical work. Like small G-proteins, to which they are related, kinesins execute a program of active site conformational changes that cleaves the terminal phosphate from an NTP substrate.
Cross, R. A.
core   +1 more source

Leveraging mechanochemistry for sustainable polymer degradation

open access: yesPolymer journal
Over 8 billion tons of plastic have been produced to date, and a 100% reclamation recycling strategy is not foreseeable. This review summarizes how the mechanochemistry of polymers may contribute to a sustainable polymer future by controlling the ...
Simay Aydonat   +8 more
semanticscholar   +1 more source

Multi‐Responsive Dendrimer‐Hyaluronic Acid Hydrogel With Lubricating and Immunoregulatory Functions for Synergistic Osteoarthritis Therapy

open access: yesAdvanced Functional Materials, EarlyView.
A hydrogel with dynamic cross‐links was formed by cross‐linking hyaluronic acid with curcumin‐preloaded, phenylboronic acid‐modified poly(amidoamine) dendrimers. This hydrogel exhibited excellent injectability and self‐healing ability, enabling controlled Cur release in response to low pH, high reactive oxygen species (ROS) generation, or mechanical ...
Junjie Liu   +9 more
wiley   +1 more source

Mechanochemical Synthesis of Lithium-Niobate-Doped Copper Oxide

open access: yesKONA Powder and Particle Journal, 2013
It is demonstrated by means of XRD, IR spectroscopy, electron microscopy, laser light scattering and measurements of the specific surface area that mechanical activation of a mixture of lithium carbonate, niobium pentoxide and copper oxide in the ...
Aleksey Alekseevich Gusev   +2 more
doaj   +1 more source

Dynamic Transition in the Structure of an Energetic Crystal during Chemical Reactions at Shock Front Prior to Detonation [PDF]

open access: yes, 2007
Mechanical stimuli in energetic materials initiate chemical reactions at shock fronts prior to detonation. Shock sensitivity measurements provide widely varying results, and quantum-mechanical calculations are unable to handle systems large enough to ...
Goddard, William A., III   +5 more
core   +1 more source

Tuning Amorphous‐Crystalline Catalytic Interfaces by Mechanochemistry: Cu‐Based Metallic Glasses Coupled with Ceria for CO Oxidation

open access: yesAdvanced Materials, EarlyView.
Ball‐milling Cu‐based metallic glasses with ceria creates a unique nanostructure where metallic glass particles are wrapped by CeO2 nanoparticles. The intimate integration triggers copper state reorganization during reaction and aging, boosting CO oxidation and COPrOx activity.
Maahin Mirzay‐Shahim   +17 more
wiley   +1 more source

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