Results 91 to 100 of about 17,423 (254)
Clinical Case ReportsKey Clinical Message We report a patient with nonimmune fetal hydrops and multiple pathologic fractures. RNA analysis revealed a novel PIEZO1 variant. This report is the first to elucidate PIEZO1's role as a critical regulator of bone mass and strength.
Elizabeth H. Ketchum +11 more
doaj +1 more source
The Anatomical Record, EarlyView.This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose +2 more
wiley +1 more source
Human digital Meissner's corpuscles are not doubly innervated
The Anatomical Record, EarlyView.Abstract Recent studies have shown that murine and avian Meissner‐like corpuscles are innervated by two distinct mechanoreceptor afferents with different functional properties. In addition, there is evidence that one subpopulation of Meissner corpuscles of monkeys is doubly innervated by mechanoreceptors and nociceptors.
Patricia Cuendias +8 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract Meissner corpuscles are rapidly adapting mechanoreceptors involved in tactile discrimination in human glabrous hand skin. Detailed information on their regional distribution and variation across age, sex, and hand side remains limited. This study mapped Meissner corpuscles in 17 phalangeal and palmar regions from 46 individuals (27 male and 19
Irene Amigo +7 more
wiley +1 more source
Mechanoreceptor of the Hearing Organ
American Journal of Biomedical Science & ResearchThe receptor that receives auditory sensations from the outside world is part of the hearing organ, it is an exteroreceptor. Receiving signals at a distance, it is a telereceptor. It is stimulated by sound wave stimuli, which are mechanical energy - it is a mechanoreceptor.
openaire +1 more source
Developmental Dynamics, EarlyView.Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm +7 more
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard +3 more
wiley +1 more source
FlexMat, EarlyView.A tactile sensor integrating indentation and protrusion sensing within a single platform enables accurate perception of object Young's modulus. This complementary architecture expands the detectable Young's modulus range to 25.8–2639.2 kPa and achieves an object recognition accuracy of 94.27%, outperforming indentation‐only (84.59%) and protrusion‐only
Jiasen Xie +9 more
wiley +1 more source
Artificial structures for human‐machine interfaces with closed‐loop interaction
FlexMat, EarlyView.Artificial structures bridge sensing and feedback in closed‐loop human‐machine interfaces by providing geometry‐enabled mechanical and functional programmability. This review maps the role of artificial structures in diverse sensing modalities and feedback strategies, and illustrates their integration into closed‐loop interaction systems, highlighting ...
Taiqi Hu +4 more
wiley +1 more source