Results 191 to 200 of about 5,291 (227)
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Investigation of Drug Delivery of Mechlorethamine (Anticancer Drug) by Si76, C76, Al38N38 Nanocages
Silicon, 2023Shereen M. Mekkey +9 more
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Intrapleural Mechlorethamine Hydrochloride Therapy for Malignant Pleural Effusion
JAMA, 1964PLEURAL EFFUSION secondary to metastatic malignant disease in pleura is a frequent occurrence. Particularly susceptible patients are those with primary breast cancer. Often the pleural effusion is the most symptomatic evidence of metastases. Systemic hormonal therapy or chemotherapy seldom alleviates the fluid accumulation and local treatment ...
J B, MARK +2 more
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Mechlorethamine-induced enhancement of radiation sensitivity of guanine
International Journal of Radiation Biology, 1996This study describes and characterizes the interactions of nitrogen mustard mechlorethamine (HN2) with guanine and the radiation sensitivity of guanine in the presence of HN2. Briefly, in an equimolar solution (0.5 mmol dm-3) the pH-dependence (pH 3.0-12.0) and time-dependence (0-36 h) of alkylation of guanine at room temperature were determined using ...
Y N, Vaishnav, C E, Swenberg
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Archives of Dermatology, 1977
Six patients with mycosis fungoides were treated with topical mechlorethamine hydrochloride for periods of two to four years. Clinical and histological studies for radiomimetic and radiodermatitis-like effects failed to demonstrate any abnormalities.
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Six patients with mycosis fungoides were treated with topical mechlorethamine hydrochloride for periods of two to four years. Clinical and histological studies for radiomimetic and radiodermatitis-like effects failed to demonstrate any abnormalities.
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Hypothermia Against Lethal Dose of Mechlorethamine
Archives of Surgery, 1961One of the problems involved in regional perfusion for cancer chemotherapy is protection of the bone marrow outside of the perfused area due to "leak" of the antitumor agent from the perfused area. Since in vitro experiments have shown that reduction in incubation temperature below 37 C depresses the antitumor effect of certain alkylating agents ...
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Archives of dermatology, 1975
Five patients with mycosis fungoides who had developed contact dermatitis to a nitrogen mustard, mechlorethamine hydrochloride, even in low concentrations (1 to 5 mg/100 ml), received daily total-body applications of extremely dilute solutions (0.01 to 0.1 mg/100 ml) of mechlorethamine.
V S, Constantine, Z Y, Fuks, E M, Farber
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Five patients with mycosis fungoides who had developed contact dermatitis to a nitrogen mustard, mechlorethamine hydrochloride, even in low concentrations (1 to 5 mg/100 ml), received daily total-body applications of extremely dilute solutions (0.01 to 0.1 mg/100 ml) of mechlorethamine.
V S, Constantine, Z Y, Fuks, E M, Farber
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Topical Mechlorethamine Therapy for Mycosis Fungoides
Archives of Dermatology, 1982Topical whole-body application of mechlorethamine hydrochloride has been shown to be efficacious in the treatment of mycosis fungoides (MF) confined to the skin. 1,2 The infiltrated plaques and tumors considerably resolve by supplementary soaks with mechlorethamine.
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33870 Mechlorethamine gel as a maintenance treatment regimen in patients with mycosis fungoides
Journal of American Academy of Dermatology, 2022E. Correia +2 more
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Topically Applied Mechlorethamine on 12 Dermatoses
Archives of Dermatology, 1962In 1959 remission occurred in a case of mycosis fungoides following the topical application of mechlorethamine hydrochloride (a nitrogen mustard) to the lesions. 1 Since then, mechlorethamine has been used topically in additional cases of mycosis fungoides and to treat several other dermatologic disorders.
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