Results 51 to 60 of about 177,701 (264)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Objectivity in Audio Description: The Norms, Research Approaches and Technological Prospects of Media Accessibility

open access: yesУправление культурой
The article analyses the concept of objectivity in audio description (AD) in the landscape of expanding media accessibility practices and tightening regulatory requirements for the provision and quality of access services for blind and visually impaired ...
Olga P. Davis
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Broadcasting and Accessibility Services Currently Offered for Deaf and Hard of Hearing Viewers by Catalan-language Broadcasters

open access: yesRevista Mediterránea de Comunicación, 2019
This article presents the main results of a user-centered study which seeks to provide an overview of accessibility services for the deaf and hard of hearing on offer from a representative sample of Catalan-language broadcasters.
Irene Tor-Carroggio, Sara Rovira-Esteva
doaj  

Filtered in/filtered out: Locative media and social accessibility in urban spaces

open access: yesStudies in Communication Sciences, 2021
Social accessibility involves the capacity of a person to be reached by other people, typically through established social networks. Locative media provide new complications to the issue of social accessibility in urban spaces. They do not connect people
Darryl A. Pieber
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

THE ROLE OF SOCIAL MEDIA ON MARKET ACCESSIBILITY AND THE BUSINESS SUCCESS OF FISH CRACKERS INDUSTRY AT SERUYAN REGANCY

open access: yesJurnal Agribest, 2019
Indonesia and in other developing countries. ICT has the ability to cut space and time limitations, especially access to communication and information, which has been a constraint to weak market access for entrepreneurs.
Rokhman Permadi, Lili Winarti
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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