Results 71 to 80 of about 192,651 (303)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Revista Mediterránea de Comunicación, 2019 This article presents the main results of a user-centered study which seeks to provide an overview of accessibility services for the deaf and hard of hearing on offer from a representative sample of Catalan-language broadcasters.
Irene Tor-Carroggio, Sara Rovira-Esteva
doaj
, 2023 During NEM summit 2023, Pilar's presentation centers around the concept of Green Media Accessibility, which entails enhancing and broadening the scope of access to environmentally conscious media. She delves into the importance of making sustainable content available to a wider audience and explores various strategies to achieve this goal.
openaire +2 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Les TIC, les médias sociaux et les étudiants et diplômés canadiens en situation de handicap
Terminal, 2014 The objective of this paper is to investigate how social media have been used by 133 students and 20 graduates who are disabled and studying in postsecondary Canadian institutions, and to analyse the accessibility of these tools.
Mai Nhu Nguyen +3 more
doaj +1 more source
Access Intimacy in Media Accessibility
Journal of Audiovisual TranslationUsing my documentary Where Memory Ends (2022) as a case study, this article tracks the journey from the standard audio description offered by the production company to the alternative approach I ended up using. An initial section on standard, compliance-based access currently implemented in Spain and the UK is followed by a discussion on alternative ...
openaire +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source