Results 81 to 90 of about 192,651 (303)

Accessibility of TV media for the dual-sensory impaired in Finland and in the UK

Finnish Journal of eHealth and eWelfare, 2019
One of the most used media is television. Almost all of us have a television set at home. Television is commonly thought also to be accessible, and for most of us, it seems to be so. However, there are people who cannot enjoy televised programmes without
Stina Ojala, Russ Palmer, Riitta Lahtinen   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Comparative analysis of the availability of popular social networking sites

Journal of Computer Sciences Institute
In the era of growing number of Internet users and the importance of social media, ensuring the accessibility of these platforms for all audiences has become a crucial aspect of digital inclusion.
Maciej Ciukaj, Maria Skublewska-Paszkowska   +1 more
doaj   +1 more source

The Role of Management Practices of Higher Education Institutions in Knowledge Storage and Knowledge Accessibility

Journal of Management and Research, 2019
This study aims to explore the management practices of Higher Education Institutions (HEIs) with regard to knowledge storage and knowledge accessibility. Data were gathered from public sector HEIs in Peshawar using semi-structured interviews.
Obaid Afridi, Shabana Gul, Muhammad Naeem   +2 more
doaj   +1 more source

E-learning accessibility practices within higher education: a review

, 2003
The 2001 Special Educational Needs and Disability Act (SENDA) made it an offence for educational institutions to discriminate against a disabled person by treating him or her less favourably than others for a reason relating to their disability.
Seale, Jane K.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Decolonising Media Accessibility

Journal of Audiovisual Translation
In this article, we explore the different forms that accessibility can take, both in theory and in practice, focusing on filmmaking and live events. We question the role and responsibility that we, as humans, have in determining how collaboration and participation can be successful within the research process, in bringing creativity and difference to ...
Kate Dangerfield, Zoe Moores, Pablo Romero Fresco   +2 more
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Impact of Digital Media on Daily Rhythms: Intrapersonal Diversification and Interpersonal Differentiation

International Journal of Communication, 2022
Digital media are popularly regarded as one of the central identifiers of postmodern life. However, systematic examinations that address how digital media and their development affect lives and contribute to social change are lacking.
Yixin Zhou, Jonathan J. H. Zhu
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source