Results 81 to 90 of about 4,586,937 (332)

Accessibility of TV media for the dual-sensory impaired in Finland and in the UK

open access: yesFinnish Journal of eHealth and eWelfare, 2019
One of the most used media is television. Almost all of us have a television set at home. Television is commonly thought also to be accessible, and for most of us, it seems to be so. However, there are people who cannot enjoy televised programmes without
Stina Ojala   +2 more
doaj   +1 more source

Guidelines for Accessibility to Microblogging: an Integral Approach [PDF]

open access: yes, 2011
Microblogging is one of the most popular user-generated media, hence its accessibility has a large impact for users. However, the accessibility of this medium is poor in practice, due to the combination of bad practices by different agents ranging from ...
Martín García, Yod Samuel   +2 more
core  

Locking Out the Mother Corp: Nationalism and Popular Imaginings of Public Service Broadcasting in the Print News Media [PDF]

open access: yes, 2007
Early promoters of public-service broadcasting (PSB) in Canada emphasized its democratic and nationalist merit. Of these twin pillars, only nationalism appears to still be standing.
Ferguson, Sue
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Role of Management Practices of Higher Education Institutions in Knowledge Storage and Knowledge Accessibility

open access: yesJournal of Management and Research, 2019
This study aims to explore the management practices of Higher Education Institutions (HEIs) with regard to knowledge storage and knowledge accessibility. Data were gathered from public sector HEIs in Peshawar using semi-structured interviews.
Obaid Afridi   +2 more
doaj   +1 more source

La inclusión de la accesibilidad en comunicación audiovisual dentro de los estudios de traducción audiovisual [PDF]

open access: yes, 2005
En el contexto de los esfuerzos institucionales realizados para incorporar a las personas con discapacidad a la sociedad, la accesibilidad en los medios de comunicación es aún una asignatura pendiente.
Orero, Pilar
core  

High-throughput chromatin accessibility profiling at single-cell resolution. [PDF]

open access: yes, 2018
Here we develop a high-throughput single-cell ATAC-seq (assay for transposition of accessible chromatin) method to measure physical access to DNA in whole cells.
Bostick, Magnolia   +9 more
core   +3 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Improving transitions in acute stroke patients discharged to home: the Michigan stroke transitions trial (MISTT) protocol

open access: yesBMC Neurology, 2017
Background For some stroke patients and caregivers, navigating the transition between hospital discharge and returning home is associated with substantial psychosocial and health-related challenges.
Mathew J. Reeves   +7 more
doaj   +1 more source

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