Results 81 to 90 of about 4,334,118 (337)
International Journal of Environmental Research and Public Health, 2020 Spatial accessibility to general hospitals is an important indicator of the convenience and ability of residents to obtain medical services. Therefore, developing a model for measuring accessibility to general hospitals by multiple transportation modes ...
Tianlu Qian +4 more
semanticscholar +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Journal of Management and Research, 2019 This study aims to explore the management practices of Higher Education Institutions (HEIs) with regard to knowledge storage and knowledge accessibility. Data were gathered from public sector HEIs in Peshawar using semi-structured interviews.
Obaid Afridi +2 more
doaj +1 more source
High-throughput chromatin accessibility profiling at single-cell resolution. [PDF]
, 2018 Here we develop a high-throughput single-cell ATAC-seq (assay for transposition of accessible chromatin) method to measure physical access to DNA in whole cells.
Bostick, Magnolia +9 more
core +3 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
BMC Neurology, 2017 Background For some stroke patients and caregivers, navigating the transition between hospital discharge and returning home is associated with substantial psychosocial and health-related challenges.
Mathew J. Reeves +7 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
La inclusión de la accesibilidad en comunicación audiovisual dentro de los estudios de traducción audiovisual [PDF]
, 2005 En el contexto de los esfuerzos institucionales realizados para incorporar a las personas con discapacidad a la sociedad, la accesibilidad en los medios de comunicación es aún una asignatura pendiente.
Orero, Pilar
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Revista Mediterránea de Comunicación, 2019 This article presents the main results of a user-centered study which seeks to provide an overview of accessibility services for the deaf and hard of hearing on offer from a representative sample of Catalan-language broadcasters.
Irene Tor-Carroggio, Sara Rovira-Esteva
doaj