Results 91 to 100 of about 932,965 (310)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Refugee Resettlement and Integration in Germany: Analysis of Media Discourse [PDF]
, 2019 Refugees are among the most discussed and debated topics worldwide; the massive movement of refugees and asylum seekers facing the world today is the largest since the end of the second world war. The United Nations High Commissioner for Refugees (UNHCR)
O\u27Neil, Dylan T.
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
L’argumentation dans le discours d’information médiatique
Argumentation et Analyse du Discours, 2011 This paper aims at contributing to the development of argumentation studies in the field of media discourse, and within this perspective, it presents two main complementary objectives.
Wander Emediato
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Girls and the Media: Girlhood Studies Agenda and Prospects in Italy [PDF]
, 2017 Within the Italian context, girlhood studies can hardly be considered a specific field: adolescence and gender construction in Italy have historically been investigated by sociology and psychology, although, in recent years, media studies have also ...
Romana Ando'
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Meat substitutes in Media Discourse
International Journal of Food StudiesShifting from meat consumption is critical for future dietary evolution. Mainstream newspapers and social media are the leading platforms for expressing this opinion. By analysing the media discourse, the proponents of the shift from meat, to plant-based
Wenxuan Guo
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Graphic-Stylistic Expressivity in Media Discourse
SHS Web of Conferences, 2018 The article deals with the analysis of graphic-stylistic means of the language, such as punctuation, functioning in modern English based on the language material of literary and media texts (on-line site of The Guardian).
Ryabova Marina Yu.
doaj +1 more source