Results 81 to 90 of about 942,723 (307)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Subjectivity Discourse of Indigenous Peoples Self Media in Taiwan

open access: yesEmerging Media
In recent years, Taiwan's grassroots Indigenous alternative media has seen the rise of a significant number of Indigenous online social media platforms.
Fu Yueh Lin
doaj   +1 more source

Spanish media discourse: quid novum?

open access: yesИбероамериканские тетради, 2017
The article focuses on the evolution of the Spanish media discourse which reflects and verbalizes mentality, modeling the world around and creating mentality and culture of the society.
Marina Larionova
doaj   +1 more source

Girls and the Media: Girlhood Studies Agenda and Prospects in Italy [PDF]

open access: yes, 2017
Within the Italian context, girlhood studies can hardly be considered a specific field: adolescence and gender construction in Italy have historically been investigated by sociology and psychology, although, in recent years, media studies have also ...
Romana Ando'
core  

Museums as disseminators of niche knowledge: Universality in accessibility for all [PDF]

open access: yes, 2019
Accessibility has faced several challenges within audiovisual translation Studies and gained great opportunities for its establishment as a methodologically and theoretically well-founded discipline. Initially conceived as a set of services and practices
Rizzo A
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Media Discourse as a Basic Notion of Medialinguistics [PDF]

open access: yes, 2013
The article deals with media discourse as a set of processes and products of language activities in mass communication sphere in all diversity and complexity of their ...
Черниш, О. А.
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Une éthique du discours médiatique est-elle possible ?

open access: yesCommunication, 2010
This article offers an insightful reflection on the enunciative positioning of media discourse and its ethical implications. In problematizing further the question of media discourse, the author proposes what could be an ethics for the media and media ...
Patrick Charaudeau
doaj   +1 more source

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