Results 91 to 100 of about 18,136,290 (245)
Discourse, Politics and Media in Contemporary China
, 2014 After three and a half decades of economic reforms, radical changes have occurred in all aspects of life in China. In an authoritarian society, these changes are mediated significantly through the power of language, carefully controlled by the political ...
Paul Chilton, Hailong Tian, Qing Cao
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Media Discourse Representation and Interaction
A lively and accessible study of media and discourse.Intro -- Contents -- Acknowledgements -- Transcription conventions -- Part One: Key issues in analysing media discourse -- 1 Introduction: media and discourse -- 2 Reconfigurations -- 3 Texts and ...
Alia, Valerie., Talbot, Mary.
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Discourse In and Through the Media Recontextualizing and Reconceptualizing Expert Discourse
This book is a result of the 2013 CLAVIER Conference held in Modena in November 2013, and includes a selection of the papers presented on that occasion. As the title suggests, this volume encourages cross-generic and cross-disciplinary investigations, in
Mazzi, Davide. +2 more
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Introduction: Social Media Discourse, (Dis)Identifications and Diversities
, 2017 The focus in this volume is on social media discourse, (dis)identifications and diversities. It demonstrates how particular ways of mobilizing verbal, discursive and other semiotic resources serve as means for identity work (Bucholtz, 2003 ...
Westinen, Elina +3 more
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Crises on Languages and LiteratureOnline news media such as Kompas.com, has become a dominant source of information for the public. In this context, news becomes one of the main forms of discourse that influences public opinion and views on important issues, public figures, and socio ...
Aris Romadhon
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source