Results 51 to 60 of about 3,812,995 (305)
International Journal of Conflict and Violence, 2019 The networked structure of the internet facilitates the dissemination of extremist messages and often makes removal impossible. Equipping media users with critical (preventive) skills appears a more promising strategy than trying to block any exposure to
Josephine B. Schmitt +3 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
International Journal of Conflict and Violence, 2018 The networked structure of the internet facilitates the dissemination of extremist messages and often makes removal impossible. Equipping media users with critical (preventive) skills appears a more promising strategy than trying to block any exposure to
Josephine B. Schmitt +3 more
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Journal of Curriculum Studies跨文化設計能力是指設計者具有文化適切性的設計能力，本研究以東部一所大 學的學生為對象，運用質性訪談輔以作品分析的方式，探究其透過參與大學社會責任計畫，以原住民族社區文化為主題的動畫影片製作過程中之跨文化設計能力學習經驗。研究發現，學生習得之跨文化設計能力包括：展現跨文化的尊重與探究態度，也能運用適切的探究、溝通及合作等設計所需技術，將習得之原住民族文化知識內容融入作品中。也因與在地社區文化的真實連結，跨文化的碰撞刺激了學生創意及思考，而創作出的作品亦可提供社區作為宣傳行銷之用。因此 ...
劉淳泓 Chun-Hung Liu +1 more
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Learning to generate emotional music correlated with music structure features
Cognitive Computation and Systems, 2022 Music can be regarded as an art of expressing inner feelings. However, most of the existing networks for music generation ignore the analysis of its emotional expression.
Lin Ma +4 more
doaj +1 more source
Media education technologies in developing students' professional competence [PDF]
, 2010 While pervasive healthcare systems bear the potential to provide patients with a new quality of medical homecare, the complexity of such systems raises fundamental questions of behavior, communication and technology acceptance.
Biletskyi, V. S. +2 more
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source