Results 71 to 80 of about 647,621 (267)

Harnessing the Power of Virtual Reality Experiences as Social Situation of Development to Enrich the Professional Experiences of Early Childhood Pre-Service Teachers

open access: yesEducation Sciences
Professional experiences are vital in teacher education programmes, especially in early childhood teacher education programmes, as this allows pre-service teachers (PSTs) to apply their theoretical knowledge in real-world settings.
Queena Lee, Anamika Devi, Jennifer Cutri
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Political media and political globalization Convergence and correlation

open access: yesالأستاذ, 2018
    The present world is witnessing strong structural indicators that reflect the interrelationship between political media and political globalization.
Dr. Haitham Nima Rahim Al - Azzawi
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Media Education

open access: yesEncyclopedia
Media Education is an educational discipline focused on critical and conscious engagement with media and their languages. Regarded as complex cultural artifacts, it serves as a preparatory phase aimed at developing interpretative and critical skills regarding the media themselves.
Michele Domenico Todino, Stefano Di Tore
openaire   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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