Results 91 to 100 of about 910,538 (316)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Political media and political globalization Convergence and correlation

open access: yesالأستاذ, 2018
    The present world is witnessing strong structural indicators that reflect the interrelationship between political media and political globalization.
Dr. Haitham Nima Rahim Al - Azzawi
doaj   +1 more source

Media Literacy Education - A discussion about Media education in the Western countries, Europe and Sweden

open access: yes, 2010
Media Education is perhaps even more important today as more and more students have practical access to a variety of media both at home and in school.
Oxstrand, Barbro,
core  

Indian Media Education for Social Responsibility- A Critical Study [PDF]

open access: yes, 2011
The paper begins with pro’s and con’s of Globalization, particularly for Indian setting. The advent of maximized automation, an offshoot of globalized economy resulting in the dent into conventional vocations & local culture, along with its ...
Ravi, B.K.
core  

Bringing Media Literacy Education into the School Curriculum: A Trilevel Adoption of Innovation Model

open access: yes, 2016
This study views media literacy education as an educational innovation and examines what factors affect the adoption of media education in secondary schools in Hong Kong.
Cheung, CK   +5 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

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