Results 61 to 70 of about 1,719,395 (305)
, 2003 Student and community leaders meet at banquet -- Peru inspires and amazes UAS group -- Egan Library wing opens to rave reviews -- Count yourself lucky -- Notice to Stafford Loan Borrowers -- VideoVersity - what is it?
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Towards a social media research methodology: Defining approaches and ethical concerns [PDF]
, 2018 Social media research and suitable methodologies and ethical approaches for analysing social media data are still emerging. This paper presents a methodology for projects using social media data alongside consideration of ethics within the social ...
Baldwin, James +3 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Framing strategic news from the perspective of media organizations in Malaysia [PDF]
, 2018 Strategic news is published news with an implied agenda without explaining the truth. Nowadays, most media are more comfortable playing tug of war in their writing than telling the truth because of the news framing process.
Adibah Ismail, +2 more
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Ethics 2.0: Social media implications for professional communicators [PDF]
, 2011 This paper examines ethical implications in the use of social media by professional communicators. Using its research into the experiences of New Zealand practitioners, it identifies major ethical challenges for the profession.
Toledano, Margalit, Wolland, Levarna Fay
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A Kantian Conception of Free Speech [PDF]
, 2010 In this paper I provide an interpretation of Kant’s conception of free speech. Free speech is understood as the kind of speech that is constitutive of interaction respectful of everybody’s right to freedom, and it requires what we with John Rawls may ...
Varden, Helga
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Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source