Results 111 to 120 of about 66,147 (308)

Knight News Challenge: Casting the Net Wide for Innovation [PDF]

open access: yes, 2010
Reviews the evolution of the Knight News Challenge contest for experimental projects in digital delivery of news and information to local communities, profiles winning projects and explores the grants' impact, and considers issues of ...
Christopher Connell
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Position of freelance jobs in the marketplace of Slovak Republic [PDF]

open access: yes, 2007
The special mission professions of freelance jobs in economics of SR. A basic character eristic of freelance jobs as subjects with individual unique performances. The definition of freelance jobs from European Council of Liberal Professions.
Dubcová, Gabriela   +1 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Os media sociais nas estratégias de divulgação dos fotógrafos freelancers

open access: yes, 2022
Social media today are as popular as traditional media. Their ease of use and accessibility have made them one of the preferred means for the dissemination of the most diverse situations. Social media marketing is currently part of the strategies of many companies.
openaire   +1 more source

Investigative journalism: a case for intensive care? [PDF]

open access: yes, 2009
Is Investigative Journalism in the UK dying or can a ‘Fifth Estate’ model resuscitate it? This paper is an examination of whether the American subscription and donation models such as ProPublica, Spot.US and Truthout are the way forward.
Lashmar, P
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Alea III, Iannis Xenakis in First Person, November 14, 2012 [PDF]

open access: yes, 2012
This is the concert program of the Alea III, Iannis Xenakis in First Person performance on Wednesday, November 14, 2012 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts. Works performed were Dipli Ziya, Evryali,
School of Music, Boston University
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Towards Industrialized Conception and Production of Serious Games [PDF]

open access: yes, 2009
Serious Games (SGs) have experienced a tremendous outburst these last years. Video game companies have been producing fun, user-friendly SGs, but their educational value has yet to be proven.
George, Sébastien   +4 more
core   +4 more sources

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