Results 131 to 140 of about 66,147 (308)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Crime of Fraud in Vacancy of Freelance Job under the Guise of Like and Follow on Social Media

Dinasti International Journal of Education Management And Social Science
Social media as a means of communication and information exchange can now be utilized to create new jobs. However, the development of information and communication technology in the use of social media also has a negative impact, there is a group of people who are less responsible for its use, causing someone to suffer physical, psychological, and ...
Ayudhianti Pranchastika, Chazizah Gusnita   +1 more
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Fansubbing from Spanish to Chinese : organization, roles and norms in collaborative writing

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2017
Objective. This paper documents and analyzes how the members of an online community of fansubbers collaborate to subtitle Hispanic series and films in Chinese.
Zhang, Tian Leticia, Cassany, Daniel
doaj  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Perlindungan Hukum atas Penipuan Online dengan Modus Pekerjaan Freelance melalui Media Sosial ditinjau dari KUHP dan UU ITE

Arus Jurnal Sosial dan Humaniora
Penipuan online dengan modus pekerjaan freelance merupakan salah satu bentuk kejahatan siber yang semakin marak di era digital. Modus ini menggunakan media sosial untuk menawarkan pekerjaan ringan dengan janji komisi tinggi, namun berujung pada kerugian finansial korban. Permasalahan dalam penelitian ini adalah bagaimana bentuk perlindungan hukum serta
Amanda Frisila, Wasis Susetio
openaire   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Understanding Consumer’s Attitude on Fish Quality and Marketing Aspects in the Greek Market [PDF]

During the last decade the Greek fish market experienced significant changes affecting both the supply and the demand of fish. Fisheries have faced significant problems, such as overfishing and low productivity.
Batzios, Christos, Moutopoulos, D.K., Siardos, G.   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Manager Perceptions of the Impact of Consolidation on the U.K. Independent Television Production Industry [PDF]

, 2010
This paper explores the impact that consolidation has had on the UK’s Independent Television Production Industry over the past decade and how this process had affected the running of different sized production companies.
North, Steven, Oliver, John James
core