Results 101 to 110 of about 3,143,128 (262)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Seminar “Japan at the Stage of Political Turbulence”
Японские исследованияIn October 2025, the cabinet of Sanae Takaichi came to power in Japan. On October 4, she was elected President of the Liberal Democratic Party and became the first female prime minister in the history of Japan.
Streltsov Dmitry V.,, Naka Ksenia O.
doaj +1 more source
Introduction To Film And Media Studies (FMST 01) Syllabus [PDF]
, 2016 Introduction To Film And Media Studies course description: The invention of cinema at the end of the 19th century and the rapid developments of digital technologies most noticeable in our increased use of social networking tools on mini-screens mark a ...
Simon, Sunka
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Nordicom Review, 2016 In this article, I examine change and continuity in conceptions of parental agency in public debates about children’s media consumption in Scandinavia, 1945-1975.
Strandgaard Jensen Helle
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Possibilities and problems of teaching the history of the present time through media and information literacy. [PDF]
, 2016 Le système éducatif encourage une histoire positiviste, ordonnée, unilatérale et universelle; par l´incorporation de le découpage chronologique de l´histoire en quatre étapes.
Triviño Cabrera, Laura
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Rethinking Mass Communications in Norway
Nordicom Review, 2014 The present article discusses the importance of the early years of mass communications in order to understand the shaping of them – the power of creating mass media for whole nations.
Bastiansen Henrik G.
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A simplified method for calculating temperature time histories in cryogenic wind tunnels [PDF]
Average temperature time history calculations of the test media and tunnel walls for cryogenic wind tunnels have been developed. Results are in general agreement with limited preliminary experimental measurements obtained in a 13.5-inch pilot cryogenic ...
Lamb, M., Stallings, R. L., Jr.
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