Results 61 to 70 of about 319 (172)

Mechanistic insights into HipA‐mediated bacterial persistence: Role of initial cellular states and toxin expression kinetics

mLife, EarlyView.
Abstract Persistent bacteria subpopulations showing multidrug tolerance pose significant challenges to antibiotic therapy. While the HipBA toxin–antitoxin (TA) system is known to play a role in persister formation, existing studies predominantly focus on its kinase activity and intracellular regulatory pathways, with limited attention to the ...
Jing Zhao, Yixiao Xiong, Hongxia Zhao, Jin Wang, Xiaona Fang   +4 more
wiley   +1 more source

Time‐Resolved Effects of Cold Atmospheric Plasma on E. coli GW‐AmxH19 Transcriptome and Proteome in an Emulated Wastewater Environment

PROTEOMICS, EarlyView.
ABSTRACT Cold atmospheric plasma (CAP) is effective against a variety of microorganisms. Here, we described effects on an Escherichia coli strain isolated from hospital wastewater caused by treatment with physical plasma. E. coli GW‐AmxH19 was incubated in artificial wastewater and treated for 15 min with CAP.
Jörg Bernhardt, Dominik Schneider, Julia Rielicke, Susanne Sievers, Veronika Hahn, Mechthild Bömeke, Anja Poehlein, Dirk Albrecht, Juergen F. Kolb, Katharina Riedel, Rolf Daniel, Daniela Zühlke   +11 more
wiley   +1 more source

Discovery of edodine, a natural compound from Lentinula edodes with antibacterial activity for the biological control of fire blight pathogen Erwinia amylovora

Pest Management Science, EarlyView.
Novel edodine was identified from Lentinula edodes HK761, exhibiting biocontrol potential against fire blight by affecting motility, intracellular ATP level, and cell division of Erwinia amylovora. Abstract BACKGROUND In the search for biological resources with antibacterial activity against Erwinia amylovora, the culture filtrate of Lentinula edodes ...
Yeong Seok Kim, Jae Woo Han, Bomin Kim, Chunggeon Lee, Daeui Park, Jaehyuk Choi, Gyung Ja Choi, Hun Kim   +7 more
wiley   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Programmable 3D Microfluidics Reveals Motility‐Driven Antibiotic Resistance Evolution in Gradients

Small, EarlyView.
Using a programmable microfluidic platform, this study shows that bacterial motility is crucial for resistance development in heterogeneous antibiotic landscapes. Motile Escherichia coli randomly migrates along antibiotic gradients, and sufficient movement is required for resistance to emerge.
Xiaobo Li, Jianan Yin, Yanqing Song, Andrew Glidle, William Sloan, He Huang, Maggie Cusack, Cindy J. Smith, Huabing Yin   +8 more
wiley   +1 more source

An Enduring Commitment to Students: Practices to Establish, Build, and Endow Basic Needs Services

New Directions for Student Services, EarlyView.
ABSTRACT This article analyzes successful basic needs fundraising campaigns at Georgetown University and George Washington University. By comparing the founding, expansion, and endowing of each institution's basic needs services, the authors identify innovative practices for other higher education institutions to establish and grow their own basic ...
Sherry Leung, Maria C. Pajarito, Albert Ramirez, Andrew C. Sonn, Sean Watley   +4 more
wiley   +1 more source

EFEKTIVITAS MEDIA SOSIAL SEBAGAI MEDIA PROMOSI

Tirtayasa Ekonomika, 2017
This study aims to find out how effective social media is used as a means to promote products among students. The method used in this study is a qualitative method that is descriptive research and tends to use analysis. There were eight students who were made as respondents.
openaire   +2 more sources

Photocatalytic and Biotechnological Strategies for Remediation of Persistent Organic Pollutants: Mechanisms, Toxicity, and Antimicrobial Perspectives

Environmental Toxicology, EarlyView.
ABSTRACT Persistent organic pollutants (POPs) pose significant ecological and human health risks due to their persistence, bioaccumulation, toxicity, and global distribution. Conventional remediation methods are often inadequate for achieving complete mineralization, demonstrating the need for advanced and substantial approaches.
Viola O. Okechukwu, Patrick B. Njobeh, Jonathan O. Okonkwo   +2 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Kesadaran UMKM Terhadap Agensi Media Sosial Dalam Meningkatkan Engagement Media Sosial

RIGGS: Journal of Artificial Intelligence and Digital Business
Perkembangan teknologi digital menjadikan media sosial sebagai sarana strategis bagi Usaha Mikro, Kecil, dan Menengah (UMKM) dalam membangun brand awareness dan meningkatkan engagement dengan audiens, namun tingkat kesadaran UMKM terhadap pemanfaatan jasa agensi media sosial masih relatif rendah akibat keterbatasan pemahaman, sumber daya, serta ...
Fabiola Karina Meylani, Satria Veriansyah Wiguna   +1 more
openaire   +1 more source