Results 141 to 150 of about 48,502,445 (376)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

The Academic Study of Media Has Always Been the Study of New Media

open access: yesWestminster Papers in Communication and Culture, 2017
Has amnesia been a consistent aspect of media studies? This talk argues this may be so drawing upon the insight of Peters and Kleis Nielson (2013: 257) that new media are things we don’t know what to do with and ‘media we do not know how to talk about’. A sense of crisis always accomponies this sense of the newness of the media. Key moments have shaped
openaire   +3 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Sports Journalists as Agents of Change in Nordic Countries

open access: yesMedia and Communication
Sports Journalists as Agents of Change: Shifting Political Goalposts in Nordic Countries identifies and describes changes prevalent in political narratives of sports journalism. Although tensions between professional autonomy and commercial influences in
Anders Graver Knudsen   +2 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Thermo-elasticity for anisotropic media in higher dimensions

open access: yes, 2011
In this note we develop tools to study the Cauchy problem for the system of thermo-elasticity in higher dimensions. The theory is developed for general homogeneous anisotropic media under non-degeneracy conditions.
A. Bannini   +22 more
core   +1 more source

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