Results 101 to 110 of about 6,828,197 (312)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

THE USE OF INSTRUCTIONAL MEDIA IN THE TEACHING OF ENGLISH OF THE FIFTH YEARS STUDENTS OF SDN PURWOSARI I PASURUAN IN THE ACADEMIC YEAR 2004/2005 [PDF]

open access: yes, 2005
A teacher should have a good and interesting technique in teaching. One of them can be done by using various instructional media. This research was meant to describe the kinds and the use of instructional media in the teaching of English in the ...
IKAYANTI, KRISNA
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Media Use in Estonia

open access: yesNordicom Review, 2006
The article gives an overview of general trends in media use in Estonia over the last 15 years, making some comparisons with Nordic countries.
Vihalemm Peeter
doaj   +1 more source

The Relationship of Fans’ Sports-Team Identification and Facebook Usage to Purchase of Team Products [PDF]

open access: yes, 2015
Social media has become a regular direct marketing component for sports teams. This study explores the link between team identification and use of a professional sports team’s social-media channels.
Griffin, Robert J.   +2 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Symbolic Spaces of Everyday Life

open access: yesNordicom Review, 2006
This article presents an analysis of the role of the media in the symbolic construction of work and leisure at home. Dealing with individuals who represent a post-industrial and cultural labour market and who work mainly at home, the analysis focuses ...
Bengtsson Stina
doaj   +1 more source

Children's Media Use and Sleep Problems: Issues and Unanswered Questions [PDF]

open access: yes, 2008
Reviews research on the potential effect of new trends in children's media use on sleep and the effect of inadequate sleep on attention, learning, cognitive development, and psychiatric and physical health.

core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Social Media Enters the Mainstream: Report on the Use of Social Media in Advancement, 2014 [PDF]

open access: yes, 2014
Social media use is becoming increasingly engrained in the work of alumni relations, communications, fundraising and marketing professionals at educational institutions, according to results cited in a new white paper.
Jennifer Mack, Michael Stoner
core  

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