Results 121 to 130 of about 6,828,197 (312)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Pediatric ReportsBackground/Objectives: This study evaluates a media prevention program conducted in elementary schools. Methods: A one-week media program, carried out with fourth graders in Leipzig, Germany, was evaluated using a non-randomized controlled cluster design.
Tanja Poulain +3 more
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Cogent Social SciencesThis study investigated the mediational role of conviction in the relationship between media use and affective polarization, and the moderating role of age in this mediation. An online survey of 1,026 Korean adults examined ideological and gender issues.
Eun-Yeong Na
doaj +1 more source
Meerdere schermen in de huiskamer: een onderzoek naar simultaan mediagebruik [PDF]
, 2012 Today’s (home) media environment is becoming increasingly saturated. Smartphones, tablets and laptops enter our living rooms and possibly alter our television viewing experience.
Courtois, Cédric +2 more
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Media fragment indexing using social media
, 2014 With more and more video resources shared on the Web, the practice of sharing a video object from a certain time point (deep-linking) has been implemented by many video sharing platforms. With so many media fragments created, annotated and shared, however, indexing video objects on a fine-grained level on the Web scale is still not implemented by major
Li, Yunjia +3 more
openaire +1 more source
California Voter Consumption of Media on Government and Politics [PDF]
, 2013 The results of our recent survey of California voters shows that they maintain a robust interest in getting the information they need to make decisions about elections and public policy issues. The data show an electorate that remains an avid consumer of
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Making connections and promoting the profession: social media use by World Federation of Occupational Therapy member organisations [PDF]
, 2016 BACKGROUND: World Federation of Occupational Therapists (WFOT) member organisations comprise 77 national occupational therapy organisations across the world.
Bodell, Sarah +8 more
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