Results 131 to 140 of about 22,462 (202)

Altered grid-like coding in early blind people

Nature Communications
Cognitive maps in the hippocampal-entorhinal system are central for the representation of both spatial and non-spatial relationships. Although this system, especially in humans, heavily relies on vision, the role of visual experience in shaping the ...
Federica Sigismondi, Yangwen Xu, Mattia Silvestri, Roberto Bottini   +3 more
doaj   +1 more source

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

MedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy, Thị Hằng Giang Phan, Ali Hussein Eid, Paola Maccioccu, Stefania Camboni, Gavino Casu, Anna Maria Posadino, Roberta Giordo, Gianfranco Pintus   +8 more
wiley   +1 more source

Biomarker‐Based Diagnosis and Care Pathways for Alzheimer's Disease in the Era of Disease‐Modifying Treatments: A Consensus Statement by Belgian Experts

European Journal of Neurology, Volume 33, Issue 8, August 2026.
ABSTRACT Background The recent approval of disease‐modifying therapies (DMTs) for early Alzheimer's disease (AD) marks a major shift in clinical practice. Biomarker confirmation of amyloid pathology is now required alongside clinical assessment, and blood‐based tests are improving accessibility.
Tim Van Langenhove, Sara Van Mossevelde, Marijke Miatton, Jan De Lepeleire, Rose Bruffaerts, Jean Christophe Bier, Kurt Segers, Jurn Verschraegen, Mirko Petrovic, Manfredi Ventura, Haroun Jedidi, Ingo Beyer, Eric Mormont, Rik Vandenberghe, Aline Delva, Christian Gilles, Donatienne Van Weehaeghe, Gaëtane Picard, Peter De Deyn, Mélanie Strauss, Evert Thiery, Eric Salmon, Gert Cypers, Joris Vlaemynck, Katrin Gillis, Jan Versijpt, Maria Bjerke, Anne Sieben, Bernard Hanseeuw, Sebastiaan Engelborghs, Olivier Deryck, on behalf of the BeDeCo members   +31 more
wiley   +1 more source

The medial entorhinal cortex is necessary for the stimulus control over hippocampal place fields by distal, but not proximal, landmarks. [PDF]

Hippocampus, 2023
Allison EAMA, Moore JW, Arkell D, Thomas J, Dudchenko PA, Wood ER.   +5 more
europepmc   +1 more source

Gait Impairment and Alzheimer's Disease Pathology: A Narrative Review on Mechanistic Links

Geriatrics &Gerontology International, Volume 26, Issue 8, August 2026.
Gait impairment and AD‐related pathology may be linked through shared risks, preclinical AD changes, feedback effects of persistent gait dysfunction, and life‐course susceptibility, underscoring the importance of maintaining brain–body health across the lifespan. ABSTRACT In older adults, gait has emerged as an important indicator of overall health and
Ryota Sakurai, Manuel Montero‐Odasso
wiley   +1 more source

Structural Heterogeneity of TDP‐43 Fragments in Alzheimer's Disease and Primary Age‐Related Tauopathy by Artificial Intelligence (AI)–Based 3D Segmentation

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
Immunostaining of anti‐phosphorylated TDP‐43 (pTDP‐43), TDP‐43 C‐terminal fragment (TDP‐43 C) and TDP‐43 N‐terminal fragment (TDP‐N), combined with an AI‐based object recognition, reconstruction and automatic 3D morphometric analysis pipeline in limbic regions revealed that distinct TDP‐43 fragment aggregation patterns, underscoring region‐specific ...
Gokhan Uruk, Rodolfo G. Gatto, Nadia Hossain, Jennifer L. Whitwell, R. Ross Reichard, Keith A. Josephs   +5 more
wiley   +1 more source

Structure function relationships in medial entorhinal cortex

, 2015
In dieser Arbeit werden Struktur-Funktionsbeziehungen in der medialen entorhinalen Hirnrinde untersucht. Schicht 2 Neurone im medialen entorhinalen Cortex unterteilen sich in calbindin-positive Pyramidenzellen und calbindin-negative Sternzellen. Calbindin-positive Pyramidenzellen bündeln ihre apikalen Dendriten zusammen und formen Zellhaufen, die in ...
openaire   +1 more source

Cell-Type Specific Inhibition Controls the High-Frequency Oscillations in the Medial Entorhinal Cortex. [PDF]

Int J Mol Sci, 2022
Gurgenidze S, Bäuerle P, Schmitz D, Vida I, Gloveli T, Dugladze T.   +5 more
europepmc   +1 more source

Models of spatial representation in the medial entorhinal cortex

, 2018
High-level cognitive abilities such as memory, navigation, and decision making rely on the communication between the hippocampal formation and the neocortex. At the interface between these two brain regions is the entorhinal cortex, a multimodal association area where neurons with remarkable representations of self-location have been discovered: the ...
openaire   +1 more source

Telencephalic outputs from the medial entorhinal cortex are copied directly to the hippocampus. [PDF]

Elife, 2022
Tsoi SY, Öncül M, Svahn E, Robertson M, Bogdanowicz Z, McClure C, Sürmeli G.   +6 more
europepmc   +1 more source