Results 121 to 130 of about 24,307 (213)

Interactions between stimulus and response types are more strongly represented in the entorhinal cortex than in its upstream regions in rats

eLife, 2017
Previously we reported results which suggested that response types are critical in dissociating the lateral entorhinal cortex (LEC) from the medial entorhinal cortex (MEC) in a scene memory task (Yoo and Lee, 2017).
Eun-Hye Park, Jae-Rong Ahn, Inah Lee
doaj   +1 more source

Boundary Vector Cells Encode a Future‐Biased Spectrum of Positions in the Rat

Hippocampus, Volume 36, Issue 4, July 2026.
ABSTRACT Spatial tuning is a hallmark property of neural firing in the hippocampal formation. Yet, that tuning is often less well correlated with the instantaneous current position of an animal than it is with an integrated version of the past or future state of the animal.
Ehren Lee Newman, Inna Mashanova‐Galikova, Zoran Tiganj, Colin Lever   +3 more
wiley   +1 more source

Distinct regional patterns of synaptic vulnerability across hippocampal and parahippocampal subregions in Alzheimer's disease

Brain Pathology, Volume 36, Issue 4, July 2026.
Synaptic loss in Alzheimer's disease predominantly affects the entorhinal cortex and parahippocampal gyrus. Amyloid‐β and p‐tau pathology show global associations with synaptic density but are limited in specific subregions. Instead, axonal damage associates with synaptic loss locally and in interconnected subregions.
Maud M. A. Bouwman, Irene Frigerio, Yvon Galis‐de Graaf, Wilma D. J. van de Berg, Laura E. Jonkman   +4 more
wiley   +1 more source

Entorhinal Cortex: Antemortem Cortical Thickness and Postmortem Neurofibrillary Tangles and Amyloid Pathology [PDF]

, 2017
BACKGROUND AND PURPOSE: The entorhinal cortex, a critical gateway between the neocortex and hippocampus, is one of the earliest regions affected by Alzheimer disease-associated neurofibrillary tangle pathology.
M.S. Albert, Cabral, HJ, Desikan, RS, Bennett, DA, Dale, AM, Hess, CP, A.M. Dale, Dillon, WP, Hyman, BT, Fleischman, DA, R.J. Killiany, D.A. Fleischman, Thaker, AA, W.P. Dillon, C.P. Hess, B.D. Weinberg, S.E. Leurgans, Albert, MS, B.T. Hyman, H.J. Cabral, D.A. Bennett, A.A. Thaker, Leurgans, SE, Fischl, B, Weinberg, BD, Killiany, RJ, B. Fischl, R.S. Desikan   +27 more
core   +1 more source

Freezing of Gait Levodopa Response Pattern in Parkinson's Disease Provides Clues to Pathophysiology

European Journal of Neuroscience, Volume 64, Issue 1, July 2026.
ABSTRACT Freezing of gait (FOG) is a common and enigmatic feature of Parkinson's disease (PD) because of its episodic and unpredictable nature. It is now clear that FOG is not a monolithic phenomenon but instead exhibits substantial heterogeneity across patients, suggesting the existence of subtypes.
Stewart A. Factor, David Weinshenker, Jeanne Powell, Andrew S. Monaghan, Daniel S. Peterson, J. Lucas Mckay   +5 more
wiley   +1 more source

Electrophysiological profiles of cell-types in medial entorhinal cortex [PDF]

, 2016
This dataset shows electrophysiological profiles of different whole-cell patch-clamp recorded cell-types in the medial entorhinal cortex that receive monosynaptic input form the medial septum and diagonal band of broca.DataSheets.pdf contains an overview
Dennis Dalügge (3280521), Hiroshi Kaneko (3280527), Daniel Justus (3267087), Stefan Remy (3280533), Liudmila Sosulina (3280530), Stefanie Bothe (3280524)   +5 more
core   +1 more source

Topography of Regional Cerebral GABAA Receptor Availability in Parkinson's Disease Patients With Freezing of Gait

European Journal of Neuroscience, Volume 64, Issue 1, July 2026.
Reduced gamma‐aminobutyric acid (GABAA) receptor availability may augur a role for GABAA inverse agonists for treatment of freezing of gait in Parkinson's disease. ABSTRACT We aimed to explore the relationship between regional gamma‐aminobutyric acid (GABAA) receptor availability, measured with [11C]‐flumazenil brain positron emission tomography (PET ...
Alexander A. Hart, Prabesh Kanel, Jaimie Barr, Giulia Carli, Robert Vangel, Fotini Michalakis, Peter J. H. Scott, Stiven Roytman, Nicolaas I. Bohnen   +8 more
wiley   +1 more source

Allocentric directional processing in the rodent and human retrosplenial cortex [PDF]

, 2014
Head direction cells in the rodent brain have been investigated for a number of years, providing us with a detailed understanding of how the rodent brain codes for allocentric direction.
Robin eHayman, Robin Hayman, Hayman, Robin, Hayman, R, Rebecca Knight, Knight, Rebecca, Rebecca eKnight, Knight, R   +7 more
core   +1 more source

Distribution of calcium-binding proteins immunoreactivity in the bottlenose dolphin entorhinal cortex

Frontiers in Neuroanatomy
IntroductionThe entorhinal cortex has been shown to be involved in high-level cognitive functions in terrestrial mammals. It can be divided into two main areas: the lateral entorhinal area (LEA) and the medial entorhinal area (MEA).
Jean-Marie Graïc, Annamaria Grandis, Simona Sacchini, Claudio Tagliavia, Giulia Salamanca, Bruno Cozzi, Cristiano Bombardi   +6 more
doaj   +1 more source

Neural Organoid Models as a Platform for Studying Disease Mechanisms in Amyotrophic Lateral Sclerosis

Journal of Neurochemistry, Volume 170, Issue 7, July 2026.
Amyotrophic lateral sclerosis (ALS) involves widespread cortical pathology beyond the motor cortex. Human‐induced pluripotent stem cell‐derived neural organoids model cortical tissue in vitro and provide a physiologically relevant platform to study disease mechanisms in ALS.
Kristel N. Eigenhuis, Roberto Montoro Ferrer, R. Jeroen Pasterkamp   +2 more
wiley   +1 more source