Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford +14 more
wiley +1 more source
Functional architecture of the medial entorhinal cortex
Schicht 2 des mediale entorhinale Kortex (MEK) beinhaltet die größte Anzahl von Gitterzellen, welche durch ein hexagonales Aktivitätsmuster während räumlicher Exploration gekennzeichnet sind. In dieser Arbeit wurde gezeigt, dass spezielle Pyramidenzellen, die das Protein Calbindin exprimieren, in einem hexagonalen Gitter im Gehirn der Ratte angeordnet ...
openaire +1 more source
Optogenetic activation of dopamine D1 receptors in island cells of medial entorhinal cortex inhibits temporal association learning. [PDF]
Yokose J +3 more
europepmc +1 more source
Global and Voxel‐Wise Brain Age Prediction Analyses Following Perinatal Stroke
ABSTRACT Perinatal stroke affects millions of individuals worldwide, often leading to lifelong complications for those who survive and who require targeted rehabilitation to limit disability. Although biological brain age prediction may be a valuable biomarker to analyze neurodevelopment following perinatal stroke and guide rehabilitation, there have ...
Ravi Amir Santiago Bullock +5 more
wiley +1 more source
Progressive Excitability Changes in the Medial Entorhinal Cortex in the 3xTg Mouse Model of Alzheimer's Disease Pathology. [PDF]
Chen L +11 more
europepmc +1 more source
External Source Monitoring and Reality Monitoring: Meta‐Analysis of fMRI Studies
We conducted an fMRI meta‐analysis showing the overlapping and unique clusters involved in external source monitoring and reality monitoring. Our results show the peculiarities of each monitoring task better defining each process. ABSTRACT Being able to remember the origin of a particular memory is for times even more important than the memory itself ...
Beatriz Martín‐Luengo +2 more
wiley +1 more source
Impaired Spatial Firing Representations of Neurons in the Medial Entorhinal Cortex of the Epileptic Rat Using Microelectrode Arrays. [PDF]
Xu Z +12 more
europepmc +1 more source
Structural MRI and 18F‐FDG‐PET reveal distinct structure‐metabolism decoupling in temporal lobe epilepsy. A presurgical machine learning model integrating these complementary radiomics with clinical features robustly predicts postoperative seizure freedom, achieving prognostic efficacy that could rival models reliant on actual resection data.
Yuming Li +15 more
wiley +1 more source
Astrocytes in Genetic Epilepsies: Supporting Actor or Key Player?
Astrocytes contribute to the pathophysiology of acquired epilepsy. However, less is known about their contribution to genetic epilepsy syndromes which often exhibit frequent comorbidity with neurodevelopmental and psychiatric disorders. Epileptic seizures are also frequently present in neurodevelopmental disorders.
Jenny Lange +4 more
wiley +1 more source
Neurogliaform cells mediate feedback inhibition in the medial entorhinal cortex. [PDF]
Szocs S +4 more
europepmc +1 more source

