Results 131 to 140 of about 71,606 (255)

APOE-mediated sex differences in microvascular pathology and AD-associated proteinopathies in the medial temporal lobe. [PDF]

Alzheimers Dement
Bax F, Oltmer J, Auger CA, Bonkhoff A, Coughlan GT, Melloni A, Jaisa-Aad M, Augustinack J, Serrano-Pozo A, Frosch MP, Greenberg SM, Gomez-Isla T, Hyman BT, van Veluw SJ, Perosa V.   +14 more
europepmc   +1 more source

Information needs of patients considering epilepsy surgery: A scoping review

Epilepsia, EarlyView.
Abstract Objective Epilepsy surgery is a recommended treatment for individuals with drug‐resistant epilepsy. However, patients often face significant challenges in decision‐making due to a lack of accessible and high‐quality information. Methods We conducted a scoping review to identify the information needs of people considering surgery for epilepsy ...
Maren Kimura, Shahab Marzoughi, Ashley Truesdale, Diane L. Lorenzetti, Colin B. Josephson, Derek Payne, Churl‐Su Kwon, Nathalie Jette   +7 more
wiley   +1 more source

Can we predict surgical outcomes: A systematic review and critical appraisal of clinical prediction models in epilepsy surgery

Epilepsia, EarlyView.
Abstract Objective Prediction models are increasingly being sought in epilepsy surgery to predict postoperative outcomes and support clinical decision‐making. Studies summarizing the evidence in this area can provide insight into the type of surgical prediction models, their methodology, and their performance and inform areas for future research.
Alyssa A. Federico, Mandavi Kashyap, Chantelle Q. Y. Lin, Karl M. Klein, Olayinka I. Arimoro, Samuel Wiebe   +5 more
wiley   +1 more source

Unique deficits in place coding across subfields of the hippocampus in a mouse model of temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Memory problems are comorbid with temporal lobe epilepsy (TLE). Animal models of TLE reveal impairments in spatial firing fields of hippocampal place cells, providing a potential neural substrate for memory problems. Each subfield of the hippocampus carries out unique aspects of spatial memory, yet little is known about how ...
Brittney L. Boublil, Margaret M. Donahue, Cathy B. Dang, Gergely Tarcsay, Laura A. Ewell   +4 more
wiley   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

Epilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara, Erwin A. van Vliet, Alessia Romagnolo, Kevin Staley, Kyle P. Lillis, Chris Dulla, David C. Henshall, Katja Kobow   +7 more
wiley   +1 more source

Pyruvate dehydrogenase autoantibodies in autoantibody‐negative patients with seizures are associated with reduced pyruvate dehydrogenase activity

Epilepsia, EarlyView.
Abstract Objective We investigated the presence and potential functional relevance of antimitochondrial autoantibodies in patients suspicious for autoimmune encephalitis (AIE) associated with psychiatric symptoms and/or seizures, who were negative for known antineuronal autoantibodies.
Annika Breuer, Chiara A. Hummel, Tobias Baumgartner, Juliane L. Berns, Afaf Milad Said, Isabel Bünger, Susanne Schoch, Gábor Zsurka, Harald Prüss, Wolfram S. Kunz, Rainer Surges, Albert J. Becker, Julika Pitsch   +12 more
wiley   +1 more source

Picture naming: Stereoelectroencephalography and connectivity insights

Epilepsia, EarlyView.
Abstract Objective This study investigates the neural substrates of picture naming (PN) using stereoelectroencephalographic (SEEG) stimulations and evaluates the contribution of white matter (WM) fascicles related to the basal temporal language area (BTLA) to the broader functional PN network.
Insafe Mezjan, Fabien Rech, Olivier Aron, Louis Maillard, Sophie Colnat‐Coulbois   +4 more
wiley   +1 more source

Medial temporal lobe atrophy is associated with age and pathologies, especially small vessel disease. [PDF]

Sci Rep
van Westen D, Stomrud E, Lorenzini L, Palmqvist S, Barkhof F, Hansson O, Spotorno N.   +6 more
europepmc   +1 more source

Fully automated three‐dimensional deep learning‐based magnetic resonance imaging segmentation of brain cavities in epilepsy surgery

Epilepsia, EarlyView.
Abstract Objective There are several clinical and research applications for determining the amount of brain tissue resected after epilepsy surgery; however, manual segmentation of postoperative magnetic resonance imaging (MRI) is imprecise and time‐consuming.
Raphael Fernandes Casseb, Brunno Machado de Campos, Wallace Souza Loos, Marcelo Eduardo Ramos Barbosa, Marina Koutsodontis Machado Alvim, Gabriel Chagas Lutfala Paulino, Enrico Ghizoni, Francesco Pucci, Samuel Worrell, Clarissa Lin Yassuda, Roberto Medeiros de Souza, Lara Jehi, Fernando Cendes   +12 more
wiley   +1 more source

Correction to "Unpacking the Medial Temporal Lobe: Separating Recollection and Familiarity". [PDF]

Hippocampus
europepmc   +1 more source