Results 141 to 150 of about 71,606 (255)

The relationships between ethnoracial identity, Aβ positivity, APOEε4, and medial temporal lobe tau PET. [PDF]

Alzheimers Dement
Wheeler KV, Tennant VR, Lee NN, Hand MW, Ganesan S, Walsh P, Tubi M, Terner JA, Hall B, Davison M, Toga AW, O'Bryant S, Clark AL, Yaffe K, Braskie MN, HABS‐HD Study Team.   +15 more
europepmc   +1 more source

High incidence of Y‐chromosome mosaicism in male and female individuals with mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy

Epilepsia, EarlyView.
Abstract Objective Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is an underrecognized pediatric cortical lesion associated with somatic X‐linked SLC35A2 variants in approximately 50% of individuals. The genetic etiology in individuals without detectable SLC35A2 mutations remains undefined, which limits
Erica Cecchini, Till Hartlieb, Ahmed Gaballa, Katja Kobow, Mitali Katoch, Paraskevi Chasani, Georgia Vasileiou, Wiebke Hofer, Lea M. Reisch, Manfred Kudernatsch, Christian G. Bien, Roland Coras, Ingmar Blümcke, Lucas Hoffmann   +13 more
wiley   +1 more source

Are comorbid sleep disorders associated with higher risk for sudden unexpected death in epilepsy? Observations from a Canadian epilepsy clinic

Epilepsia, EarlyView.
Abstract Objective Pooled mortality is nearly three times higher in people with epilepsy (PWE). Approximately 80% of sudden unexpected death in epilepsy (SUDEP) events occur during sleep, and primary sleep disorders are prevalent in the general population and PWE.
Marion Lazaj, Ellen Lee, Tristan Derry, Helen Driver, Gavin P. Winston, Lysa Boissé Lomax, Ana Johnson, Garima Shukla   +7 more
wiley   +1 more source

Presurgical magnetoencephalography‐derived network control metrics distinguish successful hippocampal resection vs sparing in temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Surgical decision‐making in temporal lobe epilepsy (TLE) faces a critical challenge in determining whether the hippocampus can be safely spared during anterior temporal resection, particularly when surgery involves the language‐dominant hemisphere.
Guhan Seshadri NP, Himanshu Kumar, Neha Sara John, Andreas V. Alexopoulos, Richard C. Burgess, Hiroatsu Murakami, Balu Krishnan   +6 more
wiley   +1 more source

Modeling temporal lobe epilepsy with hippocampal sclerosis in rats using the selective neurotoxin stable substance P‐saporin

Epilepsia, EarlyView.
On day 0 adult male and female rats were injected with Stable Substance P‐Saporin (SSP‐SAP) at 4 unilateral sites along the longitudinal axis of the dentate gyrus. Rats exhibited spontaneous electrographic and behavioral reactive seizures between days 4‐6. There was a progressive loss of CA1 and CA3 neurons and a progressive increase in astrocytes over
Srijal Gupta, Mitchell T. Kesler, Morris H. Scantlebury, Robert S. Sloviter, G. Campbell Teskey   +4 more
wiley   +1 more source

Machine learning for missing data imputation in Alzheimer's research: predicting medial temporal lobe dynamic flexibility. [PDF]

Cogn Neurodyn
Moallemian S, Saghafi A, Deshpande R, Perez JM, Budak M, Fausto BA, Elahi FM, Gluck MA.   +7 more
europepmc   +1 more source

Individual‐specific resting‐state networks predict language dominance in drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to reliably estimate individual‐specific resting‐state cortical networks and determine whether language network topography can predict task‐based language dominance in drug‐resistant epilepsy. Methods We utilized a multisession hierarchical Bayesian model (MS‐HBM) trained on drug‐resistant epilepsy patients ...
Mervyn Jun Rui Lim, Shaoshi Zhang, Shreya Pande, Aihuiping Xue, Ru Kong, Kareem Zaghloul, Sara Inati, B. T. Thomas Yeo   +7 more
wiley   +1 more source

A learning-evoked slow-oscillatory architecture paces population activity for offline reactivation across the human medial temporal lobe. [PDF]

Neuron
Causse AA, Curot J, Lopes-Dos-Santos V, Nunes-da-Silva R, Barron HC, Dornier V, Denuelle M, De Barros A, Sol JC, Lotterie JA, Lehongre K, Fernandez-Vidal S, Frazzini V, Navarro V, Valton L, Barbeau EJ, Denison T, Reddy L, Dupret D.   +18 more
europepmc   +1 more source

Ultrafast oscillations in the human brain and their functional significance

Epilepsia, EarlyView.
Abstract Objective The upper frequency limit of human brain activity remains unknown. Using ultrahigh sampling rate (≥20 kHz) intracranial microelectroencephalography, this study aimed to systematically explore and quantitatively characterize brain field oscillations beyond the established high‐frequency oscillation range (>2 kHz), and to determine ...
Milan Brázdil, Vojtěch Trávníček, Jonathan Curot, Martin Pail, Monika Służewska‐Niedźwiedź, Robert Roman, Filip Plešinger, Emmanuel Barbeau, Michal Kucewicz, Petr Klimeš, Jan Cimbálník, Pavel Jurák, William C. Stacey, Gregory A. Worrell   +13 more
wiley   +1 more source