Imaging memory in temporal lobe epilepsy: predicting the effects of temporal lobe resection [PDF]
Functional magnetic resonance imaging can demonstrate the functional anatomy of cognitive processes. In patients with refractory temporal lobe epilepsy, evaluation of preoperative verbal and visual memory function is important as anterior temporal lobe ...
Bonelli, S. B. +7 more
core +2 more sources
Three-dimensional mapping of neurofibrillary tangle burden in the human medial temporal lobe.
Tau protein neurofibrillary tangles are closely linked to neuronal/synaptic loss and cognitive decline in Alzheimer's disease and related dementias. Our knowledge of the pattern of neurofibrillary tangle progression in the human brain, critical to the ...
Paul Yushkevich +39 more
semanticscholar +1 more source
Hippocampal neuron loss and astrogliosis in medial temporal lobe epileptic patients with mental disorders [PDF]
Hippocampal neuron loss and reactive astrogliosis are pathological features of medial temporal lobe epilepsy. Here, the expression of hippocampal astrogliosis-associated genes are studied in subjects with medial temporal lobe epilepsy and mental ...
Jun Lu, Hongxing Huang, Qichang Zeng, Xinmei Zhang, Min Xu, Yi Cai, Qin Wang, Yahui Huang, Qiong Peng, Lanqiuzi Deng
doaj +1 more source
Functional coupling between CA3 and laterobasal amygdala supports schema dependent memory formation
The medial temporal lobe drives semantic congruence dependent memory formation. However, the exact roles of hippocampal subfields and surrounding brain regions remain unclear.
Mushfa Yousuf +3 more
doaj +1 more source
White matter hyperintensities are a marker of small vessel cerebrovascular disease that are strongly related to cognition in older adults. Similarly, medial temporal lobe atrophy is well-documented in aging and Alzheimer’s disease and is associated with ...
Batool Rizvi +16 more
doaj +1 more source
Medial temporal lobe connectivity and its associations with cognition in early Alzheimer’s disease
Berron et al. show that functional connectivity between the medial temporal lobe and the anterior-temporal system is reduced in the earliest stages of Alzheimer’s disease, before connectivity with the posterior-medial system is affected.
D. Berron +4 more
semanticscholar +1 more source
Functional MRI during hippocampal deep brain stimulation in the healthy rat brain [PDF]
Deep Brain Stimulation (DBS) is a promising treatment for neurological and psychiatric disorders. The mechanism of action and the effects of electrical fields administered to the brain by means of an electrode remain to be elucidated.
Boon, Paul +9 more
core +19 more sources
Contribution of mixed pathology to medial temporal lobe atrophy in Alzheimer's disease
It is unclear how different proteinopathies (tau, transactive response DNA‐binding protein 43 [TDP‐43], amyloid β [Aβ], and α‐synuclein) contribute to atrophy within medial temporal lobe (MTL) subregions in Alzheimer's disease (AD).
R. Flores +11 more
semanticscholar +1 more source
Progesterone shapes medial temporal lobe volume across the human menstrual cycle
The rhythmic production of sex steroid hormones is a central feature of the mammalian endocrine system. In rodents and nonhuman primates, sex hormones are powerful regulators of hippocampal subfield morphology.
Caitlin M. Taylor +6 more
semanticscholar +1 more source

