Results 131 to 140 of about 3,476,975 (297)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Median computation in graphs using consensus strategies

open access: yes
Following the Majority Strategy in graphs, other consensus strategies, namely Plurality Strategy, Hill Climbing and Steepest Ascent Hill Climbing strategies on graphs are discussed as methods for the computation of median sets of profiles.
Changat, M.   +2 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Axiomatic characterization of the absolute median on cube-free median networks

open access: yes
In Vohra, European J. Operational Research 90 (1996) 78 – 84, a characterization of the absolute median of a tree network using three simple axioms is presented. This note extends that result from tree networks to cube-free median networks.
Mulder, H.M., Vohra, R.V.
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

An empirical application of the median voter model and of the interest group influence model to the Portuguese and Galician municipalities [PDF]

open access: yes
The analysis of the median voter hypothesis indicates that a more realistic comprehension of local public choice might be achieved with the opening of the median voter model to the interst group influence hypothesis.
José Cruz
core  

Median-lethal concentration (LC50) for imidacloprid on diets varying in phytochemical content after 24 and 48 hours.

open access: yes, 2018
Median-lethal concentration (LC50) for imidacloprid on diets varying in phytochemical content after 24 and 48 hours.
Ling-Hsiu Liao (5921093)   +2 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Median-joining network of 57 D-loop haplotypes of Dentex dentex (S3 Table).

open access: yes, 2018
Each circle represents a haplotype and its size is proportional to haplotype frequency. Colors indicate different geographic origin (red: Eastern Mediterranean, yellow: Western Mediterranean, blue: Atlantic).
Alexiane Viret (5743157)   +11 more
core   +1 more source

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