Results 151 to 160 of about 3,898,923 (290)
, 2018 In the figure, the circles represent haplotypes, with areas proportional to their frequencies, and the colors indicate the original population. The median vectors (absent or extinct haplotypes) are shown in white.
Ândrea Kelly Ribeiro-dos-Santos (5979146) +7 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Analysis of Facility Protection Strategies Against Uncertain Numbers of Attacks: The Stochastic R-Interdiction Median Problem with Fortification [PDF]
, 2008 We present the Stochastic R-Interdiction Median Problem with Fortification (S-RIMF). This model optimally allocates defensive resources among facilities to minimize the worst-case impact of an intentional disruption. Since the extent of terrorist attacks
Liberatore, Federico +5 more
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
, 2013 Les 21 et 22 mai prochains se tiendra à l'université de Reims une conférence internationale de synthèse sur le programme ANR MeDIan, sous le titre "Méditerranée et océan Indien : deux mondes en miroir".
median
core
Median-Unbiased Estimation in DF-GLS Regressions and the PPP Puzzle [PDF]
Using median-unbiased estimation based on Augmented-Dickey-Fuller (ADF) regressions, recent research has questioned the validity of Rogoff's "remarkable consensus" of 3-5 year half-lives of deviations from PPP. The confidence intervals of these half-life
Lopez, C., Murray, C J., Papell, D H.
core +2 more sources
A United Probabilistic Approach to Minimising the Sum of Absolute Values
EkonometriaAim: Introduce a novel method for minimizing functions in the form of a sum of absolute values. Methodology: The sum of absolute values can be standardized so that the sum of the coefficients equals 1.
Changyong Feng +3 more
doaj