A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Highly Selective NaV1.8 Inhibitor JKN2306 in Healthy Chinese Subjects. [PDF]
Yang Y +14 more
europepmc +1 more source
ABSTRACT Introduction Total intravenous anesthesia (TIVA) in children has gained popularity due to potential advantages, including decreased respiratory adverse events, postoperative nausea and vomiting, and emergence agitation. British Columbia Children's Hospital (BCCH) has a reputation for TIVA use, training, and advocacy, including intravenous ...
Nicholas West +4 more
wiley +1 more source
Ultrasound-Guided Modified Clavipectoral Fascial Plane Block With Superficial Cervical Plexus Block for Midshaft Clavicular Surgery: A Prospective Randomized Controlled Trial. [PDF]
Zhang Z, Xu J, Huang Z, Sun G.
europepmc +1 more source
ABSTRACT Background Epidural analgesia is commonly used for pain control after major lower‐limb orthopedic surgery in children, but it is associated with a risk of postoperative urinary retention. Consequently, urinary catheters are often placed and left in situ for the full duration of epidural analgesia, despite the potential risks of prolonged ...
Idan Katz +6 more
wiley +1 more source
Preoperative Tapentadol Enhances the Depth of Anesthesia-Induced Sleep, Recovery Profile, and Serotonergic Modulation in Dogs Undergoing Ovariectomy with Propofol-Sevoflurane Anesthesia. [PDF]
Costa GL +5 more
europepmc +1 more source
ABSTRACT Background Intravenous lidocaine therapy (IVLT) is often used in perioperative multimodal analgesia due to its analgesic, anti‐hyperalgesic, and anti‐inflammatory effects. In adults, IVLT doses of 1–2 mg/kg/h produce plasma concentrations of 1–2 μg/mL, within the presumed therapeutic range of 1–5 μg/mL.
McKenna Postles +3 more
wiley +1 more source
ABSTRACT Objective To evaluate the effects of perioperative music interventions on emotional outcomes (preoperative anxiety, postoperative fear, emergence delirium) and related physiological parameters in children and adolescents undergoing surgery, and to examine potential effect modifiers.
Yuchen Wen +4 more
wiley +1 more source
Effect of sodium hypochlorite irrigant temperature on postoperative pain following endodontic treatment: a systematic review. [PDF]
Anna Geevarghis M +5 more
europepmc +1 more source
ABSTRACT Background Objective assessment of sedation depth in children undergoing procedural sedation while maintaining spontaneous breathing and protective reflexes can be challenging. Processed electroencephalogram (pEEG) monitoring systems such as the Narcotrend monitor may provide continuous information regarding the depth of sedation.
Hendryk Schneider +3 more
wiley +1 more source
Analgesic Efficacy and Adverse Effects of Epidural Ropivacaine Combined with Equipotent Alfentanil or Sufentanil for Labor Analgesia: A Multicenter Randomized Controlled Single-Blind Trial. [PDF]
Jiang X +26 more
europepmc +1 more source

