Results 191 to 200 of about 27,537 (233)

Liposomal bupivacaine: is it the "code" to reduce postoperative opioid consumption? [PDF]

Int J Surg
Yuan F, Yi M, Xiang B, Xiang B.
europepmc   +1 more source

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

Phytotherapy Research, EarlyView.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta, Elena Lucarini, Alessandra Toti, Maria Giovanna Cataldi, Clara Ciampi, Gina Rosalinda De Nicola, Lorenzo Di Cesare Mannelli, Carla Ghelardini   +7 more
wiley   +1 more source

Effects of Ultrasound-Guided Oblique Subcostal Transversus Abdominis Block Combined With Patient-Controlled Intravenous Analgesia on Analgesia and Early Recovery After Open Hepatectomy: A Randomized Controlled Clinical Trial. [PDF]

Clin J Pain
Wang C, Xu W, Li Y, Sun Y, Chen W, Yang W, An K.   +6 more
europepmc   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Intertransverse Process Block versus Erector Spinae Plane Block as Adjuncts to an Interpectoral Block for Breast Cancer Surgery: A Randomized Controlled Trial. [PDF]

J Pain Res
Samerchua A, Ditsatham C, Supphapipat K, Konkarn N, Leurcharusmee P, Wongmaneerung P, Owaphakorn T, Prapussarakul K, Jinadech T, Wanvoharn M.   +9 more
europepmc   +1 more source

Extrahepatic Gene Editing In Vivo Using Organic Solvent‐Free Lipid Nanoparticles

Small, EarlyView.
This article highlights a novel, organic solvent‐free lipid nanoparticle (LNP) formulation that avoids cholesterol, thereby reducing hepatic accumulation and immune activation. These BLNPs enable potent, flexible, and scalable gene delivery, supporting personalized medicine and diverse nucleic acid applications.
Michael Streiber, Na Liu, Laurianne Simon, Franziska Adermann, Vivien Bachmann, Lucas Gath, Stephanie Hoeppener, Stephanie Schubert, Oliver Werz, Vincent Lapinte, Marie Morille, Michael Bauer, Adrian T. Press, Ulrich S. Schubert, Anja Traeger   +14 more
wiley   +1 more source

Endoscopic-Assisted Peri-Root Anesthesia Provides Superior Intraoperative Analgesia Over Epidural Anesthesia in L5-S1 Interlaminar Endoscopic Discectomy. [PDF]

Orthop Surg
Chang H, Niu Y, Zhang Y, Wu Q, Sun J, Zhang D, Xu J.   +6 more
europepmc   +1 more source

In Vitro Reconstruction of Axonal Heat Sensing with a Photothermal Nerve‐on‐a‐Chip

Small, EarlyView.
A photothermal nerve‐on‐a‐chip platform is presented that enables precise, localized heating of sensory axons with simultaneous electrical recording. The system reveals millisecond‐scale dynamics of heat‐evoked neural activity and provides a new approach to study how temperature‐dependent ion channel behavior is translated into axonal firing.
Koji Sakai, Yujiro Tanaka, Riku Takahashi, Toichiro Goto, Yosuke Mizuno, Taiki Otomo, Aya Tanaka   +6 more
wiley   +1 more source

Comparison of the Effect of Ketofol and Ketodex as Procedural Sedation and Analgesia for Oocyte Retrieval during <i>In vitro</i> Fertilisation Procedures: A Randomised Controlled Pilot Study. [PDF]

J Hum Reprod Sci
Veeranki S, Jain D, Kumar S, Hussain SY, Khanna P, Kashyap L, Malhotra N, Mahey R.   +7 more
europepmc   +1 more source

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

The Chemical Record, EarlyView.
This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley   +1 more source