Results 61 to 70 of about 26,138 (325)

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

Advanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source

Efficacy and safety of apremilast and phototherapy versus phototherapy only in psoriasis vulgaris

The Journal of Dermatology, Volume 49, Issue 12, Page 1211-1220, December 2022., 2022
Abstract Phototherapy and apremilast (oral phosphodiesterase‐4 inhibitor) are well‐known in the treatment of moderate to severe psoriasis vulgaris. However, current evidence on the efficacy and safety of their combination is not sufficient. This multicenter, randomized controlled study compared the efficacy and safety between phototherapy as ...
Akimichi Morita, Yukie Yamaguchi, Chiharu Tateishi, Kyoko Ikumi, Aya Yamamoto, Haruna Nishihara, Daisuke Hayashi, Yukihiko Watanabe, Yuko Watanabe, Ayano Maruyama, Koji Masuda, Daisuke Tsuruta, Norito Katoh   +12 more
wiley   +1 more source

Endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUSTBNA): Solitary fibrous tumor of the mediastinum

Liječnički vjesnik, 2023
A solitary fibrous tumor is a rare type of mesenchymal neoplasm with a described incidence of 1 new case in a million people a year. It is slowgrowing tumor that can arise almost anywhere in the body, usually with benign characteristics with little or no
Robert Gečević, Darjan Ranilović, Ivan Marasović, Damir Vukoja, Đivo Ljubičić   +4 more
doaj   +1 more source

Risk factors for pneumonia after endoscopic laryngopharyngeal surgery in cases with prior esophageal cancer treatment

Annals of Gastroenterological Surgery, EarlyView.
This study found that the risk factors for postoperative pneumonia after endoscopic laryngopharyngeal surgery for superficial laryngopharyngeal cancer were multiple lesions and larger lesion diameter. Prior esophagectomy for esophageal cancer did not increase the incidence of pneumonia, suggesting the procedure can be safely performed with careful ...
Atsushi Nakao, Hirofumi Kawakubo, Masashi Takeuchi, Satoru Matsuda, Kazumasa Fukuda, Yuko Kitagawa   +5 more
wiley   +1 more source

BENIGN AND MALIGNANT CARDIAC AND MEDIASTINAL MASSES IN CHILDREN

Alʹmanah Kliničeskoj Mediciny, 2016
The authors have summarized their experience of surgical treatment of cardiac and mediastinal neoplasms in 24 pediatric patients who were operated and followed up from 1967 to 2012.
M. A. Martakov, V. T. Selivanenko
doaj   +1 more source

The interpretation of endobronchial ultrasound image using 3D convolutional neural network for differentiating malignant and benign mediastinal lesions [PDF]

arXiv, 2021
The purpose of this study is to differentiate malignant and benign mediastinal lesions by using the three-dimensional convolutional neural network through the endobronchial ultrasound (EBUS) image. Compared with previous study, our proposed model is robust to noise and able to fuse various imaging features and spatiotemporal features of EBUS videos ...
arxiv  

Prognostic factors for patients with esophageal cancer who achieve pathological complete response in the primary tumor after upfront chemotherapy or chemoradiotherapy

Annals of Gastroenterological Surgery, EarlyView.
Male gender and pathological lymph node metastasis are independent poor prognostic factors in patients with esophageal cancer who receive upfront treatment followed by surgery and achieved pathological complete response of the primary tumor. Among patients without pathological lymph node metastasis, the upfront chemotherapy group showed significantly ...
Masaaki Motoori, Koji Tanaka, Hiroshi Miyata, Makoto Yamasaki, Osamu Shiraishi, Atsushi Takeno, Tomoki Makino, Keijiro Sugimura, Takushi Yasuda, Yuichiro Doki   +9 more
wiley   +1 more source

Resection and a rare type of reconstruction of the superior vena cava with the left brachiocephalic vein [PDF]

Folia Medica
Resection and reconstruction of the superior vena cava (SVC) are required in a selected group of patients with anterior mediastinal tumors and lung neoplasms. We present the case of a 63-year-old woman who underwent invasive type B2 thymoma resection and
Georgi Yankov, Magdalena Alexieva, Evgeni Mekov, Rosen Petkov   +3 more
doaj   +3 more sources

Salvage esophagectomy for unresectable locally advanced esophageal squamous cell carcinoma: Significant or not?

Annals of Gastroenterological Surgery, EarlyView.
Abstract We reviewed the current status and perspectives on salvage esophagectomy for initially unresectable locally advanced esophageal squamous cell carcinoma (ESCC) in the era of minimally invasive surgery and immunotherapy. Although the standard treatment for these patients is definitive chemoradiotherapy (CRT), the complete response rate to CRT ...
Hiroshi Saeki, Makoto Sakai, Takayoshi Watanabe, Makoto Sohda, Ken Shirabe   +4 more
wiley   +1 more source

Cell Germ primary tumor of mediastinum (seminoma of mediastinum)

Archivo Médico de Camagüey, 2019
Background: the anterior mediastinal germ cell tumor is a formation of neoplastic cells located in the mediastinum. They are formed by congenital defects in the embryonic stage by migration of the primordial germ cell and dermal cells that are within the
René Hernández-Benedicto, Rafael Pila-Pérez, Pedro Rosales-Torres   +2 more
doaj