Results 61 to 70 of about 50,573 (248)

Preoperative Prediction of Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma Using Arterial Enhancement Fraction Derived From Dual‐Layer Spectral CT

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate the diagnostic value of arterial enhancement fraction (AEF) derived from dual‐layer detector spectral CT (DLCT) in preoperative assessment of cervical lymph node metastasis in patients with papillary thyroid carcinoma (PTC), and to compare its performance with other spectral CT quantitative parameters and conventional CT ...
Lili Ye, Xiangfa He, Ming Liang, Yuxin Wei, Hao Zhang, Xiaomin Liu, Xiaolin Zheng   +6 more
wiley   +1 more source

Primary leiomyosarcoma originating from the azygos vein misdiagnosed as tracheal tumor: a case report and literature review

Frontiers in Oncology
Leiomyosarcomas are uncommon mesenchymal neoplasms. Primary mediastinal leiomyosarcomas are even rarer with only a limited number of cases reported. Given the high potential for recurrence and metastasis, accurate and timely diagnosis become extremely ...
Long-fei Zhu, Yu-jun Wang, Chun-jian Zuo, Yuan-lin Deng, Bin Jiang   +4 more
doaj   +1 more source

Surgical Removal of Residual Tumor Masses in Patients Undergoing Targeted Therapy for EGFR‐Mutated Locally Advanced or Metastatic Lung Cancer

International Journal of Cancer, EarlyView.
Non‐small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations often exhibit significant tumor reduction following tyrosine kinase inhibitor (TKI) therapy. Residual tumors frequently remain, however, leading to drug resistance and disease progression.
Fedor Moiseenko, Daniil Stroyakovskiy, Evgeniy Levchenko, Mikhail Fedyanin, Albina Gabina, Ani Oganesian, Sergey Belukhin, Maria Stepanova, Ekaterina Stepanova, Elizaveta Artemyeva, Alexander Myslik, Nikita Volkov, Alexei Bogdanov, Tatiana Shuginova, Kirill Kryukov, Valeria Kheinshtein, Arif Allakhverdiev, Ivan Zaberegniy, Yana Akhmadiyarova, Mikhail Popov, Anastasiya Danilova, Dmitriy Sehniaidze, Nikita Savelov, Nikita Levchenko, Evgeniy Slugin, Olga Lopushanskaya, Ekaterina Kuligina, Svetlana Aleksakhina, Aglaya Iyevleva, Alexandr Ivantsov, Vladimir Moiseyenko, Evgeny Imyanitov   +31 more
wiley   +1 more source

Dyspnoea and restrictive lung disease due to mediastinal and pleural lipomatosis in morbid obesity

Respirology Case Reports, 2019
Dyspnoea in obese patients can be multifactorial and complex. Mediastinal and pleural lipomatosis can be associated with obesity and is usually considered asymptomatic and benign. We report an obese 39‐year‐old man who presented with progressive dyspnoea,
Jen Yuh Lim, Kim A. McAnulty, Catherina L. Chang   +2 more
doaj   +1 more source

Tumor‐Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy–Immunotherapy Combination Trials

International Journal of Cancer, EarlyView.
ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang, Hui Wang, Weiyan Tang, Kai Kang, Kateryna Onyshchenko, Taotao Huang, Dan Liu, Jianxin Xue, You Lu, Gabriele Niedermann, Ren Luo   +10 more
wiley   +1 more source

MET Expression in Upper Gastrointestinal Adenocarcinoma: Prevalence, Prognostic Impact, and Implications for Anti‐MET Antibody‐Drug Conjugate Therapy

International Journal of Cancer, EarlyView.
ABSTRACT MET is an actionable receptor tyrosine kinase, and MET‐directed antibody–drug conjugates (ADCs) have recently entered clinical practice with FDA approval in non‐small cell lung cancer and are now being evaluated across gastrointestinal malignancies, with patient selection based on MET immunohistochemistry (IHC) 3+ membranous staining at ...
Tillmann Bedau, Thomas Zander, Hans Anton Schlößer, Hakan Alakus, Onur Mustafov, Reinhard Büttner, Christiane Bruns, Alexander Quaas   +7 more
wiley   +1 more source

Institutional Learning Curve in Esophagectomy: Technical Standardization of Gastric Conduit Formation and Conduit‐Related Outcomes in 187 Consecutive Patients

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Learning curves in esophagectomy are often described in terms of procedural volume, but institutional maturation also reflects progressive standardization of reconstruction, operative choreography, and team‐based decision‐making.
Mayank Tripathi, Reshma R. Balachandran, Kumar Vineet, Dhaval Vadodaria, Vaibhav Kushwaha, Mohd Irfan Ansari, Piyush Shukla   +6 more
wiley   +1 more source

DERMACLEAR: AI‐Powered Insights Into Four Chronic Inflammatory Skin Diseases in Spain

JEADV Clinical Practice, EarlyView.
Using an AI‐enhanced analysis of electronic health records from nearly 50,000 patients, the DERMACLEAR study provides real‐world insights into the prevalence, clinical complexity, comorbidities and treatment patterns of HS, CU, PsO and AD in Spain.
Ana Giménez‐Arnau, Javier Ortiz de Frutos, Raquel Rivera‐Díaz, Lluís Puig, Jaume Notario Rosa, José Luis López‐Estebaranz, Vicente García‐Patos Briones, Ana Martín‐Santiago, José Ignacio Rojo‐Laguna, Elisabet Fernández‐Martínez, Lara Gómez‐Labrador, Esteban Daudén   +11 more
wiley   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

Obstructive shock caused by infection of a mediastinal tumor: a case report and literature review

Frontiers in Medicine
BackgroundMediastinal tumor are a category of neoplasms that arise in the central region of the thoracic cavity. The clinical manifestations of this condition are diverse and have the potential to precipitate a range of severe complications, including ...
Wenxin Wang, Luping Cheng, Xia Hu, Hong Wan, Chuanliang Pan   +4 more
doaj   +1 more source