Results 91 to 100 of about 3,741,405 (383)
The title of this paper was suggested by the confusion existing even among certainmediators about what mediation is and what it represents actually.Is mediation “a different type of justice” or, otherwise, it is “an alternative totraditional justice”?
openaire +3 more sources
Background In 2015 the increased migratory pressure in Europe posed additional challenges for healthcare providers. The aim of this study was to inform the development of a “Resource Package” to support European Union (EU) member states in improving ...
Antonio Chiarenza+4 more
doaj +1 more source
A Phylogeny-based Test of Mediation Effect in Microbiome [PDF]
Recent studies suggest that the microbiome can be an important mediator in the effect of a treatment on an outcome. Microbiome data generated from sequencing experiments contain the relative abundance of a large number of microbial taxa with their evolutionary relationships represented by a phylogenetic tree.
arxiv
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
32 pages, 3 figures, references added, minor ...
Baryakhtar, M+2 more
openaire +2 more sources
Decomposition of the Total Effect for Two Mediators: A Natural Counterfactual Interaction Effect Framework [PDF]
Mediation analysis has been used in many disciplines to explain the mechanism or process that underlies an observed relationship between an exposure variable and an outcome variable via the inclusion of mediators. Decompositions of the total causal effect of an exposure variable into effects characterizing mediation pathways and interactions have ...
arxiv
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Identification, Inference and Sensitivity Analysis for Causal Mediation Effects [PDF]
Causal mediation analysis is routinely conducted by applied researchers in a variety of disciplines. The goal of such an analysis is to investigate alternative causal mechanisms by examining the roles of intermediate variables that lie in the causal ...
K. Imai, L. Keele, Teppei Yamamoto
semanticscholar +1 more source
Causal mediation analysis with a latent mediator [PDF]
Health researchers are often interested in assessing the direct effect of a treatment or exposure on an outcome variable, as well as its indirect (or mediation) effect through an intermediate variable (or mediator). For an outcome following a nonlinear model, the mediation formula may be used to estimate causally interpretable mediation effects.
Suchitra Nelson+2 more
openaire +3 more sources
Following the outbreak of the COVID-19 pandemic, authorities have issued several guidelines to curb the pandemic's disastrous effects. However, measures' effectiveness is dependent upon people's adherence to them.
Yossi Maaravi+3 more
doaj +1 more source