Results 101 to 110 of about 1,930,794 (341)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

The Future of Nostalgia: Loss and Absence in the Age of Algorithmic Temporality

Humanities
For human beings, accepting loss and absence is a constant effort, particularly when it comes to accepting their own finitude, which becomes apparent as time passes and people leave us. This is closely linked to nostalgia and the processes of remembrance.
Silvia Pierosara
doaj   +1 more source

Implications on SUSY breaking mediation mechanisms from observing $B_s \to \mu^+ \mu^-$ and the muon $(g-2)$

, 2002
We consider $B_s \to \mu^+ \mu^-$ and the muon $(g-2)_\mu$ in various SUSY breaking mediation mechanisms. If the decay $B_s \to \mu^+ \mu^-$ is observed at Tevatron Run II with a branching ratio larger than $\sim 2 \times 10^{-8} $, the noscale ...
A. Pomarol, D. E. Kaplan, G. Isidori, G. F. Giudice, J. R. Ellis, L. Randall, N. Arkani-Hamed, P. Ko, R. Rattazzi, Seungwon Baek, T. Gherghetta, Wan Young Song, Z. Chacko, Z. Chacko   +13 more
core   +1 more source

Axion mediation

Journal of High Energy Physics, 2013
32 pages, 3 figures, references added, minor ...
Baryakhtar, M, Hardy, E, March-Russell, J   +2 more
openaire   +3 more sources

Microglia-mediated degradation of perineuronal nets promotes pain [PDF]

, 2022
Shannon Tansley, Ning Gu, Alba Ureña Guzmán, Weihua Cai, Calvin Wong, Kevin C. Lister, Einer Muñoz-Pino, Noosha Yousefpour, R. Brian Roome, Jordyn Heal, Neil Wu, Annie Castonguay, Graham Lean, Elizabeth M. Muir, Artur Kania, Masha Prager‐Khoutorsky, Ji Zhang, Christos G. Gkogkas, James W. Fawcett, Luda Diatchenko, Alfredo Ribeiro‐da‐Silva, Yves De Koninck, Jeffrey S. Mogil, Arkady Khoutorsky   +23 more
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Aggressiveness of middle and high school students and their preferred styles of behavior in conflict situations, gender aspect

Психология и право, 2018
The paper presents the results of a study of the propensity of students of the state budgetary educational institution to manifestations of various forms of aggression and their preferred strategies of behavior in conflict situations.
Shamlikashvili Ts. A., Kharitonov S. V., Pchelintseva D. N., Grafsky V. P.   +3 more
doaj   +1 more source

MARITIME MEDIATION

, 2023
This book has been elaborated in the MediMARE Mediation in Maritime Disputes Project context. MediMARE is a project financed by the EEA Grants (PT - INNOVATION-0065). The project was in place from 19th October 2021 until 30th of September 2023, and was coordinated by the University of Coimbra, through the University of Coimbra Institute for Legal ...
openaire   +2 more sources

BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly [PDF]

, 2005
Tomomi Kuwana, Lisa Bouchier‐Hayes, Jerry E. Chipuk, Christine Bonzon, Barbara Sullivan, Douglas R. Green, Donald D. Newmeyer   +6 more
openalex   +1 more source