Results 101 to 110 of about 3,741,405 (383)
FEBS Letters, EarlyView.The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet +4 more
wiley +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Psychological methods, 2013 Mediation analysis is a useful and widely employed approach to studies in the field of psychology and in the social and biomedical sciences. The contributions of this article are several-fold. First we seek to bring the developments in mediation analysis
L. Valeri, T. VanderWeele
semanticscholar +1 more source
Causal mediation analysis in presence of multiple mediators uncausally related [PDF]
, 2018 Mediation analysis aims at disentangling the effects of a treatment on an outcome through alternative causal mechanisms and has become a popular practice in biomedical and social science applications. The causal framework based on counterfactuals is currently the standard approach to mediation, with important methodological advances introduced in the ...
arxiv +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Media Theory, 2020 This introduction to a special issue of Media Theory on Mediating Presents contextualises the thematic focus and outlines the central arguments of the contributions. It suggests it is both productive and necessary to think together ‘the present’ and mediation to understand how various interlocking aspects of socio-cultural life are currently produced ...
Coleman, Rebecca, Paasonen, Susanna
openaire +4 more sources
TERMINOLOGÍA EN EL DISCURSO POLÍTICO: ALCANCE DE LA DIMENSIÓN COGNITIVO-SOCIAL
Studia Universitatis Babeş-Bolyai. PhilologiaTerminology in Political Discourse: The Impact of Its Cognitive-Social Dimension. The aim of the present article is to compare the terminology used in oral political discourse and that produced on Twitter in the context of COVID-19 in Spain, in order to
Beatriz GUERRERO GARCÍA
doaj +1 more source
Strengthening Social Justice in Informal Dispute Resolution Processes Through Cultural Competence
The Windsor Yearbook of Access to Justice, 2009 Professor Voyvodic’s call for cultural competence as an ethical requirement challenges perceptions of the legal profession as inherently and necessarily morally neutral.
Gemma Smyth
doaj +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
A Mediator’s Reflection on Family Mediation in a Recession [PDF]
Journal of Mediation & Applied Conflict Analysis, 2014 This article focusses on the personal reflections of an experienced family mediator. It looks at how, in 2014, the changed economic environment has impacted on the practice of family mediation, in particular the impact on areas such as option development. The challenge is for clients even where there is agreement between them to find workable solutions
openaire +2 more sources