Results 111 to 120 of about 1,894,725 (339)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Narratives from the margins of the state: resisting the politics of exceptionality in the Comuna 13

open access: yesOñati Socio-Legal Series, 2018
This article questions the implementation of the “state of exception” in marginal urban areas of Colombia. In so doing, it takes as a case study the military operations carried out in 2002, in Comuna 13, an urban district of Medellín.
Gustavo Rojas-Páez
doaj  

Aggressiveness of middle and high school students and their preferred styles of behavior in conflict situations, gender aspect

open access: yesПсихология и право, 2018
The paper presents the results of a study of the propensity of students of the state budgetary educational institution to manifestations of various forms of aggression and their preferred strategies of behavior in conflict situations.
Shamlikashvili Ts. A.   +3 more
doaj   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Cross-cultural localisation of Serbian tourist destinations' websites: cases of websites of tourism organisations of Belgrade, Novi Sad and Niš [PDF]

open access: yesAnali Ekonomskog fakulteta u Subotici
Tourism and culture are inextricably linked. Visiting another country with a different culture gives tourists the opportunity to gain different perspectives and enjoy the destination as well.
Stojiljković Aleksandra   +1 more
doaj   +1 more source

Calcium-mediated stabilisation of soil organic carbon [PDF]

open access: hybrid, 2017
Mike C. Rowley   +2 more
openalex   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Is it time for a global legal framework in Belgium? [PDF]

open access: yes, 2018
Environmental mediation continues to develop and evolve in different jurisdictions across the world in order to prevent potential environmental conflicts or to resolve the conflicts while avoiding the inherent drawbacks of an adjudicated solution.
Van Hoorick, Geert   +2 more
core   +1 more source

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