This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
The relationship between cognitive function and quality of life in older hypertension patients: a parallel mediation effect of frailty and medication discrepancies. [PDF]
Zhou L +7 more
europepmc +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
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Understanding autistic identity contingencies: The chain mediation effect of autism acceptance and loneliness in ableist microaggressions and social camouflage. [PDF]
Guan S +10 more
europepmc +1 more source
Daily sitting time and hyperuricemia in US adults: A dose-response association with the mediation effect of renal function-related indicators (NHANES 2007-2018). [PDF]
Li L, Wang F, Guo Q.
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Association between outdoor physical activity and positive mental health in adolescence: estimating the mediation effect of autonomy, competence and relatedness. [PDF]
Drapeau C +5 more
europepmc +1 more source
The relationship between physical activity and mental health among university students: a chain mediation effect of self-efficacy and emotion regulation. [PDF]
Wang J +5 more
europepmc +1 more source
Association of dietary index for gut microbiota and sarcopenia: the mediation effect of body roundness index. [PDF]
Li S +8 more
europepmc +1 more source
Mediation Effect of Relaxin in Cerebrospinal Fluid on the Association Between Smoking and Sleep. [PDF]
Xu Z +13 more
europepmc +1 more source
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The Effect of Noninvariance on the Estimation of the Mediated Effect in the Two-Wave Mediation Model
Structural Equation Modeling: A Multidisciplinary Journal, 2022The two-wave mediation model is the most suitable model for examining mediation effects in a randomized intervention and includes measures taken at pretest and posttest. When using self-report measures, the meaning of responses may change for the treatment group over the course of the intervention and result in noninvariance across groups at posttest ...
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