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Immunity: Plants as Effective Mediators
Critical Reviews in Food Science and Nutrition, 2014In the domain of nutrition, exploring the diet-health linkages is major area of research. The outcomes of such interventions led to widespread acceptance of functional and nutraceutical foods; however, augmenting immunity is a major concern of dietary regimens.
M Tauseef, Sultan +3 more
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Immune-Complex-Mediated Biologic Effects
New England Journal of Medicine, 1981COMPLEXES of antigen and antibody (immune complexes) are capable of causing inflammatory injury.1 Many human diseases can now be attributed to the presence of immune complexes in tissues. Some examples are systemic lupus erythematosus, acute and chronic glomerulonephritis, rheumatoid arthritis, vasculitis, and tissue injury associated with a variety of
R C, Wiggins, C G, Cochrane
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Spinally mediated opioid antidiarrheal effects
European Journal of Pharmacology, 1991To assess the role of opioid receptors in the spinal cord in regulation of functions of the intestinal mucosa in a secretory model, we evaluated the ability of i.t. administered mu (PL017), delta (DPDPE) and kappa (U50,488H) selective opioid agonists to inhibit diarrhea produced in mice by an injection of prostaglandin E2 (PGE2) (200 micrograms/mouse ...
P K, Lemcke, J E, Shook, T F, Burks
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Promoting Effective Workplace Mediation
2016Initial research on workplace mediation focused on styles and tactics a mediator should use to conduct a successful mediation. Attention has shifted to the question which strategies and tactics are most appropriate and effective given certain mediation situations, organizational circumstances, and dispute as well as disputant characteristics.
Bollen, Katalien +2 more
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Journal of Professional Issues in Engineering Education and Practice, 2006
Mediation is becoming the premier method of resolving disputes within the construction industry. The linchpin to the mediation process is the mediator. An effective mediator may make the difference between mediation success or failure. Yet, considering the importance of an effective mediator, there is a dearth of information as to the attributes of one
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Mediation is becoming the premier method of resolving disputes within the construction industry. The linchpin to the mediation process is the mediator. An effective mediator may make the difference between mediation success or failure. Yet, considering the importance of an effective mediator, there is a dearth of information as to the attributes of one
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Nebivolol: Endothelium-Mediated Vasodilating Effect
Journal of Cardiovascular Pharmacology, 2001Nebivolol, a racemic mixture of (S,R,R,R) and (R,S,S,S) enantiomers, is the most beta1-selective adrenoceptor antagonist currently available for clinical use. However, its haemodynamic effects differ from those of classical beta-adrenoceptor antagonists as a result of a vasodilating action.
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Nonplatelet-mediated effects of aspirin
Drugs of Today, 2002Aspirin has nonplatelet-mediated effects that contribute to its efficacy in the primary and secondary prevention of coronary events. These include antiarrhythmic effects, as shown in animal studies, and antiatherosclerotic effects related to increase in nitric oxide synthesis/activity and reduction in inflammatory mediators.
Y Wady, Aude, J L, Mehta
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Statistical assessment of mediational effects for logistic mediational models
Statistics in Medicine, 2004AbstractThe concept of mediation has broad applications in medical health studies. Although the statistical assessment of a mediational effect under the normal assumption has been well established in linear structural equation models (SEM), it has not been extended to the general case where normality is not a usual assumption. In this paper, we propose
Bin, Huang +3 more
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Estimation of the mediation effect with a binary mediator
Statistics in Medicine, 2006AbstractA mediator acts as a third variable in the causal pathway between a risk factor and an outcome. In this paper, we consider the estimation of the mediation effect when the mediator is a binary variable. We give a precise definition of the mediation effect and examine asymptotic properties of five different estimators of the mediation effect. Our
Yan, Li +2 more
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CGRP-mediated cardiovascular effect of nitroglycerin
Medical Hypotheses, 2003Organic nitrates, including nitroglycerin, produce vascular relaxation by releasing nitric oxide in vascular tissues near the plasma member of smooth muscle cells of veins and arteries. Calcitonin gene-related peptide (CGRP), a major transmitter in capsaicin-sensitive sensory nerves, is widely distributed in cardiovascular tissues and the release of ...
Yuan Jian, Li, Yan Hua, Du
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