Results 131 to 140 of about 6,996 (305)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The Age of Deep Mediatisation and Slovenian Literature
Ars & HumanitasThe evaluation of a literary work is a continuous, multifaceted process, which takes place through a wide range of diverse individual actions and social and institutional activities. The complexity of this process has deepened with the transition to the
Tina Kozin
doaj +1 more source
Alto al SIMCE : the campaign against standardized testing in Chile [PDF]
, 2018 This article describes the Alto al SIMCE (Stop SIMCE) campaign which aims to end the national standardized tests in Chile. In the context of the mobilizations for education in Chile, this campaign was successful in publicly and massively questioning the ...
Brossi, Lionel +2 more
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
[Professional responsibility in obstetrics in Morocco: analyzes of litigation files between 2015-2018]. [PDF]
Pan Afr Med J, 2022 Boubess I, Bezad R, Alami MH.
europepmc +1 more source
Towards the 2017 French election: Socialist and Republican nominees from the selection to the presidential election [PDF]
, 2017 In France, primaries have become an important part of French party system. Recently, the process, used by different parties, has been opened also to sympathisers.
De Luca, Marino
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Colombia: the case of citizen movement of the February 4th - 2008. Facebook : polarization or participation? [PDF]
, 2009 El centro del artículo es el estudio del grupo de Facebook: “Un millón de voces contra las Farc, creado como respuesta a la fallida liberación de secuestrados por parte de la guerrilla colombiana de las Farc, ocurrido el 31 de diciembre de 2007.
Giraldo Luque, Santiago
core +1 more source