Results 261 to 270 of about 5,004,571 (383)

Mediating Mediatized Realities

openaire   +2 more sources

Evaluating segregated school attendance as a mediator of geographic inequities in late-life cognitive function: evidence from the Study of Healthy Aging in African Americans (STAR). [PDF]

Alzheimers Dement
Gutierrez S, Whitmer RA, George KM, Peterson RL, Thomas MD, Lor Y, Allen IE, Barnes LL, Glymour MM, Torres JM, Gilsanz P.   +10 more
europepmc   +1 more source

The Relation Between Career Compromise and Occupational Engagement Behavior of University Students: A Mediation of Career Decision-Making Self-Efficacy

, 2018
문은미, 남광석
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Loop Diuretic Therapy in Severe Aortic Stenosis: Marker or Mediator of Adverse Outcomes? [PDF]

Clin Cardiol
Miyazawa M, Imamura T.
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

N-terminal half of MED14 is critical for Mediator-RNA polymerase II interaction and the resulting transcription. [PDF]

J Biol Chem
Baris Y, Jabbar J, Yozgat Y, Dinccelik-Aslan M, Cigirgan E, Erden M, Bay S, Aslan V, Cevher MA.   +8 more
europepmc   +1 more source

CRISPR/Cas9-mediated gene editing strategy to modulate Plp1 expression for Pelizaeus Merzbacher disease caused by Plp1 duplication

, 2019
Gyu‐Bon Cho, Jae Young Lee
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source