Results 51 to 60 of about 6,424 (211)

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

A Case Report: Pilonidal Sinus Management with Medical-Grade Honey

Journal of the European Wound Management Association, 2019
Due to its antimicrobial properties, medical-grade honey has shown to be effective in management of pilonidal sinus disease. This case report describes the potential therapeutic options of medical-grade honey for preventing infection and inducing wound healing.
Renée Hermanns, Byron Rodrigues
openaire   +1 more source

Magnetoelastic Cell Monitoring System for Evaluating the Effects of Surface Chemistry on the Performance of Mesenchymal Stem Cell Growth

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The recent clinical adoption of cell therapies has increased the need for more efficient, robust, and reproducible manufacturing technologies. Human mesenchymal stromal cells (hMSCs), a major component of the cell and immunotherapeutic market, remain challenging to manufacture at scale because they require surface attachment and are highly ...
William S. Skinner, Carolina Rivera‐Crespo, Eyerusalem A. Gebreyesus, Said Cifuentes, Samantha Tan, Tristen Douglas, Maribella Domenech‐Garcia, Keat Ghee Ong   +7 more
wiley   +1 more source

Comparison of In Vitro Bacterial Susceptibility to Common and Novel Equine Wound Care Dressings

Animals
Antimicrobial resistance is becoming a problem of concern in the veterinary field, necessitating the use of effective topical treatments to aid the healing of wounds.
Merrill Simpson, Dean A. Hendrickson, Doreene R. Hyatt, Sangeeta Rao   +3 more
doaj   +1 more source

Weather Action: A Study on the Industry Peer Effects of Corporate Climate Risk Information Disclosure

Business Strategy and the Environment, EarlyView.
ABSTRACT Global climate change has elevated the strategic importance of corporate climate risk disclosure, yet the role of industry peer effects in shaping such disclosure remains underexplored. Grounded in social learning theory, this study proposes an “observation–imitation–reinforcement” framework and empirically tests it using panel data on Chinese
Huer Shuang, Shenghua Lou, Renjie Luo, Jiajia Luo   +3 more
wiley   +1 more source

Personalized Gamified Learning in a Course on the Urogenital System Anatomy: Differential Effects Across Learning Preference Profiles

Clinical Anatomy, EarlyView.
ABSTRACT Personalized learning approaches adapted to individual metacognitive characteristics have demonstrated promise in Anatomy education. However, whether such benefits are uniform across learner profiles or vary systematically remains an open question with implications for individualized instructional approaches.
Mónica Stambuk‐Castellano, Alejandro Ortega‐Arranz, Anna Carrera, Enrique Verdú, R. Shane Tubbs, Joe Iwanaga, Francisco Reina   +6 more
wiley   +1 more source

Medical-grade honey as an antimicrobial agent against Helicobacter pylori: A review of current evidence

Journal of Current Biomedical Reports
Honey, a natural product of apian biology, has been recognized for its medicinal properties for centuries. The bioactive compounds present in honey, particularly those found in mono-floral varieties, exhibit antimicrobial, anti-inflammatory, and ...
Shahrzad Asgari, Parastoo Saniee
doaj   +1 more source

Medical honey for canine nasal intertrigo: A randomized, blinded, placebo-controlled, adaptive clinical trial to support antimicrobial stewardship in veterinary dermatology.

PLoS ONE, 2020
Intertrigo is a skin fold dermatitis often requiring recurrent treatment with topical antiseptics or antibiotics, which can select antimicrobial resistance.
Gabrielle Brosseau, Nadia Pagé, Caroline de Jaham, Jérôme R E Del Castillo   +3 more
doaj   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

The Efficacy of Honey for the Treatment of Perineal Wounds Following Vaginal Birth: A Narrative Review

Pharmaceuticals
Background/Objectives: During vaginal delivery, the perineum can be damaged either by episiotomy or by a spontaneous perineal tear, leading to several complications.
Isa S. Schaap, Céline M. J. G. Lardenoije, Senna J. J. M. van Riel, Niels A. J. Cremers   +3 more
doaj   +1 more source