Results 61 to 70 of about 9,030 (248)

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang   +12 more
wiley   +1 more source

Clinical usage of honey as a wound dressing: An update

open access: yes, 2004
Honey is an ancient treatment that is increasingly earning its place in modern wound care. Evidence suggests it compares with other dressings in terms of its antibacterial properties, ease of use and ability to promote a moist ...
Molan, Peter C.
core   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer   +4 more
wiley   +1 more source

‘These reforms have teeth’: The affective dimensions of teacher education policy enactment

open access: yesBritish Educational Research Journal, EarlyView.
Abstract The affective dimensions of education policy enactment have often received less attention in the research literature, especially regarding teacher education policy. This article reports on a study of the affective responses of university‐based teacher educators in England to the significant initial teacher education reforms of 2019–2022: the ...
Ian Cushing, Viv Ellis
wiley   +1 more source

Exploring the use of interactive data dashboards as a tool to support a data‐driven approach to whole‐school health improvement: Case studies from the DATAMIND project in Wales and Scotland

open access: yesBritish Educational Research Journal, EarlyView.
Abstract School is an important setting for supporting young people's healthy development and positive mental wellbeing. Recent curriculum changes in Scotland and Wales reflect this, adopting a whole‐school approach to health and wellbeing as a central pedagogical focus and responsibility of all working in the sector. Alongside education system reform,
Mary Wilson   +8 more
wiley   +1 more source

Magnetoelastic Cell Monitoring System for Evaluating the Effects of Surface Chemistry on the Performance of Mesenchymal Stem Cell Growth

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The recent clinical adoption of cell therapies has increased the need for more efficient, robust, and reproducible manufacturing technologies. Human mesenchymal stromal cells (hMSCs), a major component of the cell and immunotherapeutic market, remain challenging to manufacture at scale because they require surface attachment and are highly ...
William S. Skinner   +7 more
wiley   +1 more source

Medical honey for canine nasal intertrigo: A randomized, blinded, placebo-controlled, adaptive clinical trial to support antimicrobial stewardship in veterinary dermatology.

open access: yesPLoS ONE, 2020
Intertrigo is a skin fold dermatitis often requiring recurrent treatment with topical antiseptics or antibiotics, which can select antimicrobial resistance.
Gabrielle Brosseau   +3 more
doaj   +1 more source

Identification of components in Kazakhstan honeys that correlate with antimicrobial activity against wound and skin infecting microorganisms

open access: yesBMC Complementary Medicine and Therapies, 2021
Background Antimicrobial drug resistance is a major public health threat that can render infections including wound and skin infections untreatable. The discovery of new antimicrobials is critical.
Pauline McLoone   +9 more
doaj   +1 more source

Managed honey bee colony losses in Canada, China, Europe, Israel and Turkey, for the winters of 2008-9 and 1009-10 [PDF]

open access: yes, 2012
In 2008 the COLOSS network was formed by honey bee experts from Europe and the USA. The primary objectives set by this scientific network were to explain and to prevent large scale losses of honey bee (Apis mellifera) colonies.
Charriere, Jean-Daniel   +41 more
core   +1 more source

Personalized Gamified Learning in a Course on the Urogenital System Anatomy: Differential Effects Across Learning Preference Profiles

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Personalized learning approaches adapted to individual metacognitive characteristics have demonstrated promise in Anatomy education. However, whether such benefits are uniform across learner profiles or vary systematically remains an open question with implications for individualized instructional approaches.
Mónica Stambuk‐Castellano   +6 more
wiley   +1 more source

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