Results 171 to 180 of about 3,984,066 (343)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Effective Factors on Oral Health-Promoting Behaviors among Elementary School Students Based on BASNEF Model [PDF]

open access: yes
Effective Factors on Oral Health-Promoting Behaviors among Elementary School Students Based on BASNEF Model Naseri Pour Takallo Zohreh1, Ahmadi Tabatabaei Seyed Vahid2, Zolala Farzaneh3, Mohseni Mohabbat4* 1.
Ahmadi Tabatabaei, Seyed Vahid   +3 more
core  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

A Study of Health-Promoting Behaviors of Medical Sciences Students of Islamic Azad University of Sari, Iran 2013 [PDF]

open access: diamond, 2014
Ghahraman Mahmoodi   +4 more
openalex   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Earthquake Preparedness in Teaching Hospitals: a cross-sectional study in Yazd/ Iran [PDF]

open access: yes
Earthquake Preparedness in Teaching Hospitals: a cross-sectional study in Yazd/ Iran Abedi Mahdieh1, khanjankhani Khatere 1, Kiani Mohammad Mehdi2*, Seyed Abdel Hossein Mousavi Rigi3, Salehi Marzieh4 1 .M.Sc, School of Public Health, Shahid Sadoughi ...
Abedi, Mahdieh   +4 more
core  

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