Results 121 to 130 of about 19,687,691 (268)
Big Data Mining and AnalyticsEnsuring the general efficacy and benefit for human beings from medical Large Language Models (LLM) before real-world deployment is crucial. However, a widely accepted and accessible evaluation process for medical LLM, especially in the Chinese context ...
Mianxin Liu +18 more
doaj +1 more source
, 1950 This glass lantern slide features an aerial view of the Medical College of the State of South Carolina court in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Telemedicine System Using a High-Speed Network: Past, Present, and Future
Gut and Liver, 2009 There is no doubt that telecommunication saves a great deal of time and expense when exchanging information, and recent technological advances have increased its popularity in business and educational applications.
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
A review and systematic guide to counteracting medical data scarcity for AI applications
Computer Methods and Programs in Biomedicine UpdateArtificial intelligence has the potential to improve the scalability, objectivity, and precision of the overall healthcare system. Such improvements are possible due to the growth of medical databases and the progress of deep learning approaches, which ...
Fabian Gröger +5 more
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Laser-generated Ion Beams for Medical Applications [PDF]
, 2011 The advent of high-power laser systems paved the way for laser acceleration of ion beams. Based on theoretical simulations, we demonstrate the feasibility of laser-generated ion beams matching the strict requirements for radio-oncological applications.
openaire +2 more sources