Results 131 to 140 of about 2,015,410 (353)

4D Multi-atlas Label Fusion using Longitudinal Images

open access: yes, 2017
Longitudinal reproducibility is an essential concern in automated medical image segmentation, yet has proven to be an elusive objective as manual brain structure tracings have shown more than 10% variability.
Huo, Yuankai   +2 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

MedBench: A Comprehensive, Standardized, and Reliable Benchmarking System for Evaluating Chinese Medical Large Language Models

open access: yesBig Data Mining and Analytics
Ensuring the general efficacy and benefit for human beings from medical Large Language Models (LLM) before real-world deployment is crucial. However, a widely accepted and accessible evaluation process for medical LLM, especially in the Chinese context ...
Mianxin Liu   +18 more
doaj   +1 more source

Variable selection for logistic regression using a prediction focussed information criterion. [PDF]

open access: yes
In biostatistical practice, it is common to use information criteria as a guide for model selection. We propose new versions of the Focussed Information Criterion (FIC) for variable selection in logistic regression.
Claeskens, Gerda   +2 more
core  

Speech acts and medical records: The ontological nexus [PDF]

open access: yes, 2004
Despite the recent advances in information and communication technology that have increased our ability to store and circulate information, the task of ensuring that the right sorts of information gets to the right sorts of people remains.
Smith, Barry, Vizenor, Lowell
core   +1 more source

Construction and application of medication reminder system: intelligent generation of universal medication schedule

open access: yesBioData Mining
Abstract Background Patients with chronic conditions need multiple medications daily to manage their condition. However, most patients have poor compliance, which affects the effectiveness of treatment. To address these challenges, we establish a medication reminder system for the intelligent generation of universal ...
Hangxing Huang   +8 more
openaire   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Telemedicine System Using a High-Speed Network: Past, Present, and Future

open access: yesGut and Liver, 2009
There is no doubt that telecommunication saves a great deal of time and expense when exchanging information, and recent technological advances have increased its popularity in business and educational applications.
doaj   +1 more source

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