Results 101 to 110 of about 2,015,410 (353)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Risk Evaluation of EMT and Inflammation in Metastatic Pancreatic Cancer Cells Following Plasma Treatment

Frontiers in Physics, 2020
The requirements for new technologies to serve as anticancer agents go far beyond their toxicity potential. Novel applications also need to be safe on a molecular and patient level.
Eric Freund, Eric Freund, Chiara Spadola, Anke Schmidt, Angela Privat-Maldonado, Annemie Bogaerts, Thomas von Woedtke, Thomas von Woedtke, Klaus-Dieter Weltmann, Claus-Dieter Heidecke, Lars-Ivo Partecke, Lars-Ivo Partecke, André Käding, Sander Bekeschus   +13 more
doaj   +1 more source

Shape deformation analysis from the optimal control viewpoint [PDF]

, 2014
A crucial problem in shape deformation analysis is to determine a deformation of a given shape into another one, which is optimal for a certain cost. It has a number of applications in particular in medical imaging.
Arguillere, Sylvain, Trouvé, Alain, Trélat, Emmanuel, Younes, Laurent   +3 more
core   +2 more sources

Tree-based generational feature selection in medical applications

Procedia Computer Science, 2019
Abstract In many knowledge discovery experiments feature selection is obvious initial part. In the paper, some attempt to tree-based generational feature selection applications in medical data analysis is presented. This approach devotes to application of classification tree algorithm to estimate importance of attributes extracted from structure of ...
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Faculty perspectives on artificial intelligence’s adoption in the health sciences education: a multicentre survey

Frontiers in Medicine
IntroductionThe integration of artificial intelligence technology into healthcare education has been hampered by a number of difficulties. This study aimed to investigate the faculty’s familiarity and perception towards AI applications in medical ...
Eidan M. Al Zahrani, Salah H. Elsafi, Lenah D. Al Musallam, Abdulwahab H. Alharbi, Hala M. Aldossari, Ahmed M. Alomar, Zeyad S. Alkharraz   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

LINS: A general medical Q&A framework for enhancing the quality and credibility of LLM-generated responses

Nature Communications
Large language models can lighten the workload of clinicians and patients, yet their responses often include fabricated evidence, outdated knowledge, and insufficient medical specificity.
Sheng Wang, Fangyuan Zhao, Dechao Bu, Yunwei Lu, Ming Gong, Hongjie Liu, Zhaohui Yang, Xiaoxi Zeng, Zhiyuan Yuan, Baoping Wan, Jingbo Sun, Yang Wu, Lianhe Zhao, Xirun Wan, Wei Huang, Tao Wang, Mengtong Xu, Jianjun Luo, Jingjia Liu, Jianjun Zheng, Wei Zhang, Kang Zhang, Hongjia Zhang, Shu Wang, RunSheng Chen, Yi Zhao   +25 more
doaj   +1 more source

Medical faculty members’ perception of smartphones as an educational tool

BMC Medical Education, 2019
Background The rapid adoption of modern technology has changed many aspects of our life and communication; it has the power to influence and change the way we teach, learn and practice different types of professions mainly teaching and health care ...
Oqab Jabali, Munther Saeedi, Ghada Shbeitah, Abed Alkarim Ayyoub   +3 more
doaj   +1 more source